Evidence map›Paper›PMID 39873266›Full record

ArticleInternational endodontic journal2025

A novel artificial intelligence-powered tool for automated root canal segmentation in single-rooted teeth on cone-beam computed tomography.

Airton Oliveira Santos-Junior, Rocharles Cavalcante Fontenele, Frederico Sampaio Neves, Mário Tanomaru-Filho, Reinhilde Jacobs

Abstract read
In one paragraph

Article in International endodontic journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  13. [Study on dental image segmentation and automatic root canal measurement based on multi-stage deep learning using cone beam computed tomography].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Airton Oliveira Santos-JuniorDepartment of Restorative Dentistry, School of Dentistry, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.ORCID 0000-0003-1916-1675
Rocharles Cavalcante FonteneleOMFS IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, University of Leuven, Leuven, Belgium.ORCID 0000-0002-6426-9768
Frederico Sampaio NevesOMFS IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, University of Leuven, Leuven, Belgium.ORCID 0000-0001-9178-707X
Mário Tanomaru-FilhoDepartment of Restorative Dentistry, School of Dentistry, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.ORCID 0000-0002-2574-4706
Reinhilde JacobsOMFS IMPATH Research Group, Department of Imaging and Pathology, Faculty of Medicine, University of Leuven, Leuven, Belgium.ORCID 0000-0002-3461-0363

Funding

São Paulo State Research Foundation (FAPESP), Brasil 2020/11012-3São Paulo State Research Foundation (FAPESP), Brasil 2021/11496-3São Paulo State Research Foundation (FAPESP), Brasil 2022/13774-3
6 · The paper itself

Abstract

aimTo develop and validate an artificial intelligence (AI)-powered tool based on convolutional neural network (CNN) for automatic segmentation of root canals in single-rooted teeth using cone-beam computed tomography (CBCT). METHODOLOGY: A total of 69 CBCT scans were retrospectively recruited from a hospital database and acquired from two devices with varying protocols. These scans were randomly assigned to the training (n = 31, 88 teeth), validation (n = 8, 15 teeth) and testing (n = 30, 120 teeth) sets. For the training and validation data sets, each CBCT scan was imported to the Virtual Patient Creator platform, where manual segmentation of root canals was performed by two operators, establishing the ground truth. Subsequently, the AI model was tested on 30 CBCT scans (120 teeth), and the AI-generated three-dimensional (3D) virtual models were exported in standard triangle language (STL) format. Importantly, the testing data set encompassed different types of single-rooted teeth. An experienced operator evaluated the automated segmentation, and manual refinements were made to create refined 3D models (R-AI). The AI and R-AI models were compared for performance evaluation. Additionally, 30% of the testing sample was manually segmented at two different times to compare AI-based and human segmentation methods. The time taken by each segmentation method to obtain 3D models was recorded in seconds(s) for further comparison.

resultsThe AI-driven tool demonstrated highly accurate segmentation of single-rooted teeth (Dice similarity coefficient [DSC] ranging from 89% to 93%; 95% Hausdorff distance [HD] ranging from 0.10 to 0.13 mm), with no significant impact of tooth type on accuracy metrics (p > .05). The AI approach outperformed the manual method (p < .05), showing higher DSC and lower 95% HD values. In terms of time efficiency, manual segmentation required significantly more time (2262.4 ± 679.1 s) compared to R-AI (94 ± 64.7 s) and AI (41.8 ± 12.2 s) methods (p < .05), representing a 54-fold decrease.

conclusionsThe novel AI-based tool exhibited highly accurate and time-efficient performance in the automatic root canal segmentation on CBCT, surpassing the human performance.

Indexed as

Artificial IntelligenceCone-Beam Computed TomographyDental Pulp CavityTooth RootHumansImaging, Three-DimensionalNeural Networks, ComputerRetrospective Studiesartificial intelligencecone‐beam computed tomographyconvolutional neural networkendodonticsroot canal segmentationsingle‐rooted teeth

Identifiers

PMID39873266
PMCPMC11891948

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.