Evidence map›Paper›PMID 39873161›Full record

ArticleIntegrative cancer therapies

Nabil M Selim, Seham S El-Hawary, Soheir M El Zalabani, Rehab Nabil Shamma, Nariman El Sayed Mahdy, Noheir H Sherif, Khayrya A Youssif, Usama Ramadan Abdelmohsen, Mai H Mekkawy, Hanan A Fahmy

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In one paragraph

Article in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nabil M SelimFaculty of Pharmacy, Cairo University, Cairo, Egypt.
Seham S El-HawaryFaculty of Pharmacy, Cairo University, Cairo, Egypt.
Soheir M El ZalabaniFaculty of Pharmacy, Cairo University, Cairo, Egypt.
Rehab Nabil ShammaFaculty of Pharmacy, Cairo University, Cairo, Egypt.
Nariman El Sayed MahdyFaculty of Pharmacy, Cairo University, Cairo, Egypt.
Noheir H SherifNational Centre for Radiation Research and Technology, Egyptian Atomic Energy Authority, Cairo, Egypt.
Khayrya A YoussifFaculty of Pharmacy, El Saleheya El Gadida University, Cairo, Egypt.
Usama Ramadan AbdelmohsenFaculty of Pharmacy, Minia University, Minia, Egypt.
Mai H MekkawyNational Centre for Radiation Research and Technology, Egyptian Atomic Energy Authority, Cairo, Egypt.ORCID 0000-0002-1517-2548
Hanan A FahmyNational Centre for Radiation Research and Technology, Egyptian Atomic Energy Authority, Cairo, Egypt.ORCID 0000-0002-9593-9664

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesHepatocellular carcinoma (HCC) represents the third-most prevalent cancer in humans worldwide. The current study's objective is to search for the potentiality of MATERIAL AND

methodsThe metabolic composition of the bioactive extract of

resultsNE exerted remarkable cytotoxicity in comparison to the parent extract and the standard doxorubicin on the HepG2 cell line. Besides, the NE administration and/or γ-irradiation (IRR) significantly reduced the elevated alanine aminotransferase (ALT), total proteins, and albumin levels in HCC-induced rats. Likewise, the tumor markers alpha-fetoprotein (AFP) and gamma-glutamyl transferase (GGT) levels were considerably reduced in HCC rats. In addition, NE treatment before IRR significantly decreased the expression of the poly ADP ribose polymerase-1

conclusionNE of

Indexed as

Carcinoma, HepatocellularKi-67 AntigenLiver NeoplasmsPlant ExtractsPoly(ADP-ribose) Polymerase InhibitorsRadiation ToleranceAnimalsCell Line, TumorDiethylnitrosamineHep G2 CellsHumansMalePlant LeavesRadiation-Sensitizing AgentsRatsDiethylnitrosamineKi-67 AntigenPlant ExtractsPoly(ADP-ribose) Polymerase InhibitorsRadiation-Sensitizing Agentsgamma radiationhepatocellular carcinomametabolic compositionradiosensitizing effectWashingtonia robusta nanoemulsion

Identifiers

PMID39873161
PMCPMC11773528

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.