Evidence map›Paper›PMID 39873150›Full record

Trial reportFamily process2025

Family Connections: The Impact of an Education Program for Carers of Individuals With Borderline Personality Disorder in Italian Mental Health Services.

Mariangela Lanfredi, Serena Meloni, Clarissa Ferrari, Alan E Fruzzetti, Andrea Geviti, Ambra Macis, Giovanna Vanni, Giampaolo Perna, Giuseppina Diaferia, Maddalena Pinti and 3 more

2 registry-linked trialsAbstract readClinical Trial
In one paragraph

Trial report in Family process, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06074289 nacompletednot on this map

Psycho-educational Program for Family Members of People With Borderline Personality Disorder

TypeinterventionalSponsorIRCCS Centro San Giovanni di Dio FatebenefratelliRan2016 to 2018Enrolled89ConditionsFamily CaregiversArmsFamily connections program
NCT06076343 nacompletednot on this map

An Integrated Approach to Treatment of People With Borderline Personality Disorder and Their Caregivers

TypeinterventionalSponsorIRCCS Centro San Giovanni di Dio FatebenefratelliRan2019 to 2022Enrolled180ConditionsBorderline Personality DisorderArmsDBT skills-training and Family Connections interventions
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mariangela LanfrediUnit of Psychiatry, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.ORCID 0000-0001-5968-8952
Serena MeloniUnit of Psychiatry, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.ORCID 0000-0002-2134-3323
Clarissa FerrariResearch and Clinical Trials Office, Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.ORCID 0000-0002-4101-6872
Alan E FruzzettiMcLean Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Andrea GevitiService of Statistics, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.ORCID 0000-0003-0041-4142
Ambra MacisDepartment of Economics and Management, University of Brescia, Brescia, Italy.ORCID 0000-0003-0281-8570
Giovanna VanniDepartment of Clinical Neurosciences, Villa San Benedetto Menni Hospital, Hermanas Hospitalarias, Como, Italy.
Giampaolo PernaDepartment of Clinical Neurosciences, Villa San Benedetto Menni Hospital, Hermanas Hospitalarias, Como, Italy.ORCID 0000-0002-8166-0785
Giuseppina DiaferiaDepartment of Clinical Neurosciences, Villa San Benedetto Menni Hospital, Hermanas Hospitalarias, Como, Italy.
Maddalena PintiDepartment of Clinical Neurosciences, Villa San Benedetto Menni Hospital, Hermanas Hospitalarias, Como, Italy.
Giorgia OcchialiniDepartment of Mental Health, AST PU Marche, Fano, Italy.
Maria Elena RidolfiDepartment of Mental Health, AST PU Marche, Fano, Italy.
Roberta RossiUnit of Psychiatry, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.ORCID 0000-0001-8408-1124

Funding

"Bando Fondazione Comunità Bresciana-Bando BRESCIA città del noi 2016"Italian Ministry of Health ("Ricerca Corrente")
6 · The paper itself

Abstract

Borderline personality disorder (BPD) has a strong impact not only on patients' lives but also on their families. The presence of an invalidating environment is one of the key factors in the etiology of BPD. This study evaluated the impact of the Family connections (FC) program on burden, grief, and other clinical variables in 202 caregivers and identified the profiles of participants who improved/deteriorated their levels of burden and grief. Findings from generalized linear mixed models showed significant reductions in burden, grief, depression, global psychological distress, and suppressed and expressed anger after FC intervention. Two classification trees were applied to test whether improvements in burden and grief were associated with age, gender and the improvements in other clinical variables. Caregivers reporting reduced depression were more likely to improve in both burden and grief. Moreover, younger participants showing increased depression had a 72.7% probability of being part of the improvement in burden and a 66.7% probability of being part of the improvement in grief. A decrease in depression and having a younger age were associated with positive gains for caregiving burden and grief. Longitudinally, ANOVAs showed positive changes in burden and grief as well as decreased depression, global psychological distress and suppressed anger were maintained at 4-month follow-up. Present findings improve our understanding of the utility of the FC program for caregivers of people with BPD. The impact of depressive symptoms' reduction and being younger on perceived burden and grief highlight the importance of exploring additional possible moderators of outcomes in FC intervention. Trial Registration: NCT06076343; NCT06074289. Registered 10/10/2023.

Indexed as

Borderline Personality DisorderCaregiversFamily RelationsAdultDepressionFemaleGriefHumansItalyMaleMental Health ServicesMiddle Agedborderline personality disorderburdencaregiversfamily connectionsgrief

Identifiers

PMID39873150
PMCPMC11774136

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.