Evidence map›Paper›PMID 39873076›Full record

ArticleJournal of dental sciences2025

Biomineralization reaction from nanosized calcium silicate: A new method for reducing dentin hypersensitivity.

Mi-Jeong Jeon, Yu-Sung Choi, Jeong-Kil Park, Jin-Soo Ahn, Yu-Chih Chiang, Deog-Gyu Seo

Abstract read
In one paragraph

Article in Journal of dental sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Magnetic Janus Nanomotor for Dentin Hypersensitivity Treatment.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mi-Jeong JeonDepartment of Conservative Dentistry, Gangnam Severance Hospital, Yonsei University, Seoul, Republic of Korea.
Yu-Sung ChoiDepartment of Prosthodontics, College of Dentistry, Dankook University, Cheonan, Republic of Korea.
Jeong-Kil ParkDepartment of Conservative Dentistry, Dental Research Institute, Dental and Life Science Institute, School of Dentistry, Pusan National University, Yangsan, Republic of Korea.
Jin-Soo AhnDental Research Institute and Department of Biomaterials Science, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
Yu-Chih ChiangDivision of Restorative and Aesthetic Dentistry, School of Dentistry, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan.
Deog-Gyu SeoDepartment of Conservative Dentistry, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/purpose: This study assessed the ability of experimental materials consisting of dicalcium silicate (DCS) and tricalcium silicate (TCS) with nanosized particles to form intratubular crystals under phosphate-buffered saline (PBS) and the effect on dentin permeability reduction. Materials and methods: By isolating the cervical part of the extracted premolars, 195 specimens were obtained. Two experimental materials (DCS/TCS and TCS) were applied to the dentin surface by brushing and stored in PBS (n = 65). Another 65 specimens were not treated. Each group was randomly divided into five subgroups based on the PBS immersion period (1, 15, 30, 60, and 90 days, n = 10). The dentin permeability was measured, and the hydraulic conductance, Lp (%), was calculated. After acid challenge with 1 M acetic acid, Lp (%) was remeasured. Data were analyzed using two-way analysis of variance and Fisher's least significant difference test (α = 0.05). Three specimens of each subgroup were longitudinally sectioned and examined using scanning electron microscopy and a field emission-electron probe micro analyzer. Results: The Lp (%) of the experimental groups gradually decreased over time ( Conclusion: Intratubular crystals formed from the experimental materials consisted of DCS and TCS and were resistant to acid. These crystals significantly reduced dentin permeability.

Indexed as

Dentin hypersensitivityDicalcium silicateHydroxyapatiteIntratubular crystalTricalcium silicate

Identifiers

PMID39873076
PMCPMC11763565

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.