Evidence map›Paper›PMID 39872966›Full record

ArticleInternational journal of general medicine2025

Diagnostic Value of Measurements of Median Nerve Diameter at the Site of the Maximal Stenosis in Carpal Tunnel Syndrome.

Agnieszka Fryźlewicz, Gabriela Rusin, Wojciech Rudnicki, Marzena Ułamek-Kozioł, Jakub Antczak

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Article in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Carpal Tunnel Syndrome Diagnosis: A Narrative Review of Complementary Roles of Neuromuscular Ultrasound and Electrodiagnostic Studies.Medical science monitor : international medical journal of experimental and clinical research · 2026
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Agnieszka FryźlewiczDepartment of Neurology, University Hospital in Krakow, Cracow, Poland.
Gabriela RusinDepartment of Neurology, University Hospital in Krakow, Cracow, Poland.
Wojciech RudnickiDepartment of Radiology, University Hospital in Krakow, Cracow, Poland.
Marzena Ułamek-KoziołDepartment of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland.
Jakub AntczakDepartment of Neurology, Jagiellonian University Medical College, Krakow, Poland.ORCID 0000-0002-4011-6863

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Ultrasonography is increasingly used to diagnose the carpal tunnel syndrome (CTS). Most frequently, the enlargement of the nerve cross-sectional area (CSA) at the tunnel inlet serves to confirm the diagnosis. Recent research has shown that the nerve diameter is decreased within the tunnel, when measured at the level of pisiforme or capitatum. The stenosis index (SI), which uses the ratio of the diameter of median nerve at the tunnel inlet to the diameter within the tunnel (SI diameter), was proposed as the diagnostic marker of CTS. In this study, we compared the diameter of the median nerve measured at the site of maximal stenosis (DMS) between patients with CTS and controls. Additionally, we investigated the diagnostic utility of the modified SI, which uses the ratio of CSA at the inlet to the diameter within the tunnel (SI CSA). Methods: Forty-eight patients (72 hands) with CTS and 18 asymptomatic controls (28 hands) underwent electrodiagnostic testing and ultrasonography. Results: CSA at the inlet was larger in patients, whereas DMS showed only trend towards being smaller in CTS. CTS was also associated with more distal localization of maximal stenosis. Both SI diameter and SI CSA were higher in patients, however the discriminative effect of SI CSA was stronger. SI diameter, SI CSA, CSA at the inlet and DMS correlated with the electrodiagnostic severity grade of CTS. The post-hoc analysis revealed that patients with moderate and severe electrodiagnostic grade of CTS have smaller DMS, whereas patients with mild CTS did not differ from controls. Conclusion: DMS seems to have only limited diagnostic potential in mild CTS, but it may be a marker of more advanced cases. CTS may be associated with the distal shift of DMS. SI CSA may have significant diagnostic potential in CTS.

Indexed as

carpal tunnel syndromecross-sectional areanerve stenosisstenosis indexultrasound

Identifiers

PMID39872966
PMCPMC11771170

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