Evidence map›Paper›PMID 39872652›Full record

ArticleCJC open2025

Management of Patients with Myocardial Injury After Noncardiac Surgery: A Retrospective Chart Review.

Michael Ke Wang, Denise Sabac, Roshan Sadhak, Amy Ajay, Myles Benayon, Flavia K Borges, Yevin Cha, David Conen, Michael Coomber, Katherine Fuller and 14 more

Abstract read
In one paragraph

Article in CJC open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Michael Ke WangPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Denise SabacBachelor of Health Sciences Program, McMaster University, Hamilton, Ontario, Canada.
Roshan SadhakMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Amy AjayMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Myles BenayonMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Flavia K BorgesPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Yevin ChaMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
David ConenPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Michael CoomberMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Katherine FullerMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Diljit GillMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Rahul JayachandiranMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Carol KoubaeshSchool of Medicine, Newcastle University, Newcastle, United Kingdom.
Lekhini LatchupatulaMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Sabreena MoosaMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Sandra OforiPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Keerthana PasumarthiMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Ameen PatelDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Saif SamariMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Steffen BlumPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Mallika SureshMichael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.
Vikas TandonDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
P J DevereauxPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.
Maura MarcucciPopulation Health Research Institute, McMaster University, Hamilton, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Myocardial injury after noncardiac surgery (MINS) is associated with an increased incidence of cardiac morbidity and mortality. Little is known about how these patients are managed. Methods: We performed a single-centre retrospective chart review of patients referred to a postoperative clinic with the diagnosis of MINS. Patients were included if they attended the clinic at least once between September 2018 and December 2019. We extracted preoperative, in-hospital, and postdischarge data on cardiac investigations and medication use. Results: Of the 152 patients with MINS who were included, 34% had a history of coronary disease before MINS. The median peak high-sensitivity troponin I (hsTnI) level was 122 ng/L (interquartile range, 51-259), and 78% had no associated ischemic symptoms or electrocardiographic changes. Patients underwent echocardiography and nuclear stress imaging in 87% and 30% of cases, respectively. Of those who had cardiac investigations performed and no prior history of coronary artery disease, 23% (19 of 84) had ≥ 1 regional wall-motion abnormality on echocardiogram, and 39% (13 of 34) had evidence of ischemia on nuclear stress imaging. More patients were prescribed an antithrombotic and lipid-lowering drug at discharge (79%) and at their final clinic visit (86%), compared to the number before surgery (30%). A total of 57% of patients had changes made to ≥ 1 cardiovascular medication during clinic follow-up. Conclusions: Patients with MINS followed in a postoperative clinic frequently had abnormal cardiac investigations and received medical optimization. Our findings suggest that postoperative clinics may represent an opportunity for risk mitigation after MINS, a possibility that deserves further evaluation.

Identifiers

PMID39872652
PMCPMC11763853

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.