Evidence map›Paper›PMID 39872630›Full record

ArticleAtmospheric environment (Oxford, England : 1994)2023

Differential Cardiopulmonary Effects of Isoprene- versus Toluene-generated Photochemically-Aged Smog in Rats.

Samantha J Snow, Jonathan D Krug, John M Turlington, Judy E Richards, Mette C Schladweiler, Allen D Ledbetter, Todd Krantz, Charly King, M Ian Gilmour, Stephen H Gavett and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Atmospheric environment (Oxford, England : 1994), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Samantha J SnowCenter for Public Health and Environmental Assessment, Public Health and Integrated Toxicology Division, U.S. Environmental Protection Agency, 109 T.W. Alexander Dr., Research Triangle Park, NC, 27711 USA.
Jonathan D KrugCenter for Environmental Measurement and Modeling, Air Methods and Characterization Division, U.S. Environmental Protection Agency, 109 T.W. Alexander Dr., Research Triangle Park, NC, 27711 USA.
John M TurlingtonCenter for Environmental Measurement and Modeling, Air Methods and Characterization Division, U.S. Environmental Protection Agency, 109 T.W. Alexander Dr., Research Triangle Park, NC, 27711 USA.
Judy E RichardsCenter for Public Health and Environmental Assessment, Public Health and Integrated Toxicology Division, U.S. Environmental Protection Agency, 109 T.W. Alexander Dr., Research Triangle Park, NC, 27711 USA.
Mette C SchladweilerCenter for Public Health and Environmental Assessment, Public Health and Integrated Toxicology Division, U.S. Environmental Protection Agency, 109 T.W. Alexander Dr., Research Triangle Park, NC, 27711 USA.
Allen D LedbetterCenter for Public Health and Environmental Assessment, Public Health and Integrated Toxicology Division, U.S. Environmental Protection Agency, 109 T.W. Alexander Dr., Research Triangle Park, NC, 27711 USA.
Todd KrantzCenter for Public Health and Environmental Assessment, Public Health and Integrated Toxicology Division, U.S. Environmental Protection Agency, 109 T.W. Alexander Dr., Research Triangle Park, NC, 27711 USA.
Charly KingCenter for Public Health and Environmental Assessment, Public Health and Integrated Toxicology Division, U.S. Environmental Protection Agency, 109 T.W. Alexander Dr., Research Triangle Park, NC, 27711 USA.
M Ian GilmourCenter for Public Health and Environmental Assessment, Public Health and Integrated Toxicology Division, U.S. Environmental Protection Agency, 109 T.W. Alexander Dr., Research Triangle Park, NC, 27711 USA.
Stephen H GavettCenter for Public Health and Environmental Assessment, Public Health and Integrated Toxicology Division, U.S. Environmental Protection Agency, 109 T.W. Alexander Dr., Research Triangle Park, NC, 27711 USA.
Urmila P KodavantiCenter for Public Health and Environmental Assessment, Public Health and Integrated Toxicology Division, U.S. Environmental Protection Agency, 109 T.W. Alexander Dr., Research Triangle Park, NC, 27711 USA.
Aimen K FarrajCenter for Public Health and Environmental Assessment, Public Health and Integrated Toxicology Division, U.S. Environmental Protection Agency, 109 T.W. Alexander Dr., Research Triangle Park, NC, 27711 USA.
Mehdi S HazariCenter for Public Health and Environmental Assessment, Public Health and Integrated Toxicology Division, U.S. Environmental Protection Agency, 109 T.W. Alexander Dr., Research Triangle Park, NC, 27711 USA.

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

Photochemical smog is a complex mixture of primary and secondary air pollutants including secondary organic aerosols (SOA), ozone and reactive aldehydes which has been linked to increased risk of adverse cardiovascular and pulmonary responses. The components and related health effects of smog are thought to be determined both by the precursor chemicals and reaction conditions. Here we examined the difference between isoprene- (IS-) and toluene- (TS) generated smog in causing cardiopulmonary effects in rats. Wistar-Kyoto rats were exposed to either filtered air (FA) or smog for 4 hours. IS-smog contained 660ppb NO

Indexed as

cardiovascularisoprenepulmonaryratsSmogtoluene

Identifiers

PMID39872630
PMCPMC11770605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.