Evidence map›Paper›PMID 39872580›Full record

ArticleCureus2024

Descending Necrotizing Mediastinitis: A Rare Yet Lethal Complication Demanding Timely Intervention.

Anastasia Kosmidou, Panagiota Kosmidou, Ioannis Karamatzanis, Eleni Flari, Sofia Pouriki, Panagiotis Κ Nikolopoulos

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anastasia KosmidouPulmonology, Sotiria General Hospital of Thoracic Diseases, Athens, GRC.
Panagiota KosmidouOtolaryngology-Head and Neck Surgery, University of Patras Medical School, Patras, GRC.
Ioannis KaramatzanisInternal Medicine, Basildon University Hospital, Basildon, GBR.
Eleni FlariBiomedical Sciences, College of Medicine and Veterinary Medicine, Edinburgh Medical School, University of Edinburgh, Edinburgh, GBR.
Sofia PourikiIntensive Care Unit, General Chest Diseases Hospital Sotiria, Athens, GRC.
Panagiotis Κ NikolopoulosIntensive Care Unit, General Chest Diseases Hospital Sotiria, Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Descending necrotizing mediastinitis (DNM) is a rare and potentially life-threatening condition characterized by the rapid spread of infection within the mediastinum. This severe form of mediastinitis poses a significant challenge to clinicians due to its aggressive nature and potential for rapid deterioration. In this case report, we present a challenging case of descending necrotizing mediastinitis in a 39-year-old patient with persistent pyrexia and an extended hospital stay in the intensive care unit (ICU), cardiothoracic unit (CTU), and surgical intensive care unit (SICU). The step-by-step clinical course, diagnostic challenges, and therapeutic strategies will be discussed in detail. This case highlights the importance of early recognition and a comprehensive, interdisciplinary approach in managing this rare yet lethal mediastinitis.

Indexed as

descending mediastinitisdescending necrotizing mediastinitisent pathologymediastinitis managementmultidisciplinary management

Identifiers

PMID39872580
PMCPMC11770237

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.