Evidence map›Paper›PMID 39872235›Full record

ReviewJBMR plus2025

Dental manifestations of hypophosphatasia: translational and clinical advances.

Elis J Lira Dos Santos, Fatma F Mohamed, Kaitrin Kramer, Brian L Foster

Abstract readReview
In one paragraph

Review in JBMR plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. JBMR plus · 2026
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elis J Lira Dos SantosDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, 43210, United States.
Fatma F MohamedDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, 43210, United States.
Kaitrin KramerCleft Palate-Craniofacial Clinic, Nationwide Children's Hospital, Columbus, OH, 43205, United States.
Brian L FosterDivision of Biosciences, College of Dentistry, The Ohio State University, Columbus, OH, 43210, United States.ORCID https://orcid.org/0000-0003-3444-0576

Funding

Identifying Novel Mechanisms for Dentoalveolar Mineralization Defects in X-linked HypophosphatemiaR01DE032334 · NIDCR · OHIO STATE UNIVERSITY · PI Brian Lee Foster · 2022 to 2026
$2.5M
Role of tissue-nonspecific alkaline phosphatase in dentoalveolar development and diseaseR03DE028411 · NIDCR · OHIO STATE UNIVERSITY · PI FOSTER, BRIAN LEE · 2019 to 2020
$312k
NIDCR NIH HHS R01 DE032334NIDCR NIH HHS R03 DE028411
6 · The paper itself

Abstract

Hypophosphatasia (HPP) is an inherited error in metabolism resulting from loss-of-function variants in the

Indexed as

dental biologydiseases and disorders of/related to bonegenetic animal modelsmatrix mineralizationosteomalacia and ricketspreclinical studies

Identifiers

PMID39872235
PMCPMC11770227

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.