Evidence map›Paper›PMID 39872229›Full record

ArticleClinical, cosmetic and investigational dermatology2025

Local Hyperthermia Combined With Imiquimod Cleared Recalcitrant and Extensive Warts in a Patient With Systemic Lupus Erythematosus.

Gai-Hua Wang, Yang-Bin Wang, Yue-Ai Cheng, Hong-Duo Chen, Xing-Hua Gao, Rui-Qun Qi

Abstract readCase Reports
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gai-Hua Wang *Institute of Dermatology, Taiyuan City Centre Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, People's Republic of China.
Yang-Bin Wang *Department of Dermatology, the First Hospital of China Medical University, Shenyang, Liaoning Province, People's Republic of China.ORCID 0000-0003-1719-0448
Yue-Ai ChengInstitute of Dermatology, Taiyuan City Centre Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, People's Republic of China.
Hong-Duo ChenDepartment of Dermatology, the First Hospital of China Medical University, Shenyang, Liaoning Province, People's Republic of China.ORCID 0000-0003-1556-1575
Xing-Hua GaoDepartment of Dermatology, the First Hospital of China Medical University, Shenyang, Liaoning Province, People's Republic of China.
Rui-Qun QiDepartment of Dermatology, the First Hospital of China Medical University, Shenyang, Liaoning Province, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral warts, a common dermatological condition caused by human papillomavirus infection (HPV) infection, present a particular challenge for systemic lupus erythematosus (SLE) patients due to their compromised immunity, which increases the susceptibility to HPV infection and complicates treatment efforts. Imiquimod, an immunomodulatory agent, has demonstrated efficacy in managing warts. Furthermore, local hyperthermia, a non-invasive therapeutic modality, has demonstrated significant potential in the management of warts. We report the case of a SLE patient developed recalcitrant and extensive viral warts on limbs. We applied hyperthermia at 45 °C on a target lesion for 1 hour / day with imiquimod cream 3 times/week. All the lesions cleared in 8 months and there was no sign of recurrence.

Indexed as

human papillomavirushyperthermiaimmunitysystemic lupus erythematosus

Identifiers

PMID39872229
PMCPMC11771514

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.