Evidence map›Paper›PMID 39871907›Full record

ArticleWorld journal of hepatology2025

Comparison of different severity scores in correlating hemoglobin levels with the severity of hepatic decompensation: An observational study.

Himayat Ullah, Sarwat Huma, Ghulam Yasin, Muhammad Ashraf, Nafisa Tahir, Qazi Tahir Uddin, Hossam Shabana, Mostafa A R Hussein, Abdulrahman Shalaby, Mohammad Mossaad Alsayyad and 6 more

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Article in World journal of hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

16 authors.

Himayat UllahDepartment of Medicine, College of Medicine at Shaqra, Shaqra University, Shaqra 15526, Saudi Arabia.
Sarwat HumaHealth Professions Education, Health Services Academy, Islamabad 44000, Pakistan. sarwathuma007@gmail.com.
Ghulam YasinDepartment of Orthopedics, College of Medicine at Shaqra, Shaqra University, Shaqra 15526, Saudi Arabia.
Muhammad AshrafDepartment of Medicine, College of Medicine at Shaqra, Shaqra University, Shaqra 15526, Saudi Arabia.
Nafisa TahirDepartment of Medicine, NUST School of Health Sciences, Islamabad 44000, Pakistan.
Qazi Tahir UddinDepartment of Surgery, College of Medicine at Shaqra, Shaqra University, Shaqra 15526, Saudi Arabia.
Hossam ShabanaDepartment of Medicine, College of Medicine at Shaqra, Shaqra University, Shaqra 15526, Saudi Arabia.
Mostafa A R HusseinFaculty of Medicine, Al-Azhar University, Cairo 11865, Egypt.
Abdulrahman ShalabyFaculty of Medicine, Al-Azhar University, Cairo 11865, Egypt.
Mohammad Mossaad AlsayyadFaculty of Medicine for Boys, Al-Azhar University, New Damietta 34517, Egypt.
Ashraf SaidFaculty of Medicine, Al-Azhar University, Cairo 11865, Egypt.
Ali FarahatFaculty of Medicine, Al-Azhar University, Cairo 11865, Egypt.
Hani Ismail HamedFaculty of Medicine, Al-Azhar University, Cairo 11865, Egypt.
Hazem Sayed Ahmed AyoubFaculty of Medicine, Al-Azhar University, Cairo 11865, Egypt.
Mohammed S ImamFaculty of Medicine, Al-Azhar University, Cairo 11865, Egypt.
Essam ElmahdiFaculty of Medicine, Mansoura University, Mansoura 35511, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic liver disease is a growing global health problem, leading to hepatic decompensation characterized by an array of clinical and biochemical complications. Several scoring systems have been introduced in assessing the severity of hepatic decompensation with the most frequent ones are Child-Pugh score, model of end-stage liver disease (MELD) score, and MELD-Na score. Anemia is frequently observed in cirrhotic patients and is linked to worsened clinical outcomes. Although studies have explored anemia in liver disease, few have investigated the correlation of hemoglobin level with the severity of hepatic decompensation.

aimTo determine the relationship between hemoglobin levels and the severity of decompensated liver disease and comparing the strength of this correlation using the Child-Pugh, MELD, and MELD-Na scores.

methodsThis cross-sectional study was conducted at a tertiary care hospital with 652 decompensated liver disease patients enrolled in the study. Data was collected on demographics, clinical history, and laboratory findings, including hemoglobin levels, bilirubin, albumin, prothrombin time (international normalized ratio), sodium, and creatinine. The Child-Pugh, MELD, and MELD-Na scores were calculated. Statistical analysis was performed using Statistical Package for the Social Sciences version 26, and correlations between hemoglobin levels and severity scores were assessed using Spearman's correlation coefficient.

resultsThe study included 405 males (62.1%) and 247 females (37.9%) with an average age of 58.8 years. Significant inverse correlations were found between hemoglobin levels and Child-Pugh, MELD, and MELD-Na scores (

conclusionUnderstanding the correlation between hemoglobin and liver disease severity can improve patient management by offering insights into prognosis and guiding treatment decisions.

Indexed as

Child Turcotte Pugh scoreChronic liver diseaseHemoglobin levelHepatic decompensationModel of end-stage liver disease-Na scoreModel of end-stage liver disease score

Identifiers

PMID39871907
PMCPMC11736469

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.