Evidence map›Paper›PMID 39871895›Full record

ArticleWorld journal of hepatology2025

Hotspots and trends in stem cell therapy for liver fibrosis and cirrhosis: A bibliometric analysis.

Wen-Yan Zhu, Xiang Li, Jia-Ling Xie, Qin Lu, Ying-Jie Ma, Zhao-Jing Zhu, Juan Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wen-Yan ZhuChongqing Engineering Research Center of Pharmaceutical Sciences, Chongqing Medical and Pharmaceutical College, Chongqing 401331, China.
Xiang LiDepartment of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Jia-Ling XieImmunology Research Center of Medical Research Institute, Southwest University, Chongqing 402460, China.
Qin LuImmunology Research Center of Medical Research Institute, Southwest University, Chongqing 402460, China.
Ying-Jie MaOffice of Scientific Research of Army Medical Center, Army Medical University, Chongqing 400042, China.
Zhao-Jing ZhuChongqing Engineering Research Center of Pharmaceutical Sciences, Chongqing Medical and Pharmaceutical College, Chongqing 401331, China.
Juan LiuImmunology Research Center of Medical Research Institute, Southwest University, Chongqing 402460, China. dyx4@swu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiver fibrosis and cirrhosis are global medical challenges that require safe and effective treatments. In the past two decades, there has been a surge in research on stem cell therapy for liver fibrosis and cirrhosis. This study aimed to conduct a comprehensive analysis of the research hotspots and trends in this field through bibliometrics.

aimTo conduct a bibliometric analysis on hotspots and trends in stem cell therapy for treatment of liver fibrosis and cirrhosis.

methodsPublications on stem cell therapy for liver fibrosis and cirrhosis were retrieved from the Web of Science Core Collection database. The distribution and collaboration among literature, authors, countries, and institutions were analyzed visually using Excel, CiteSpace, Bibliometrix R-package, VOSviewer and Pajek software. Additionally, an investigation of keywords, burst keywords, and clusters was conducted.

resultsAs of September 20, 2024, a total of 1935 documents were retrieved dating from 2004 to 2024, with 1186 strongly relevant publications obtained after screening. China, the United States, and Japan were the major contributors in this field. Cairo University, Zhejiang University and Yamaguchi University were the major institution in this field. The journal

conclusionThese findings provide a thorough overview of stem cell therapy in the field of liver fibrosis and cirrhosis.

Indexed as

BibliometricsCirrhosisExosomesExtracellular vesiclesLiver fibrosisMesenchymal stromal cellStem cell therapy

Identifiers

PMID39871895
PMCPMC11736489

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.