Evidence map›Paper›PMID 39871516›Full record

ArticleThe British journal of psychiatry : the journal of mental science2026

Evaluating Computerised Assessment of Motor Imitation (CAMI) for identifying autism-specific difficulties not observed for attention-deficit hyperactivity disorder or neurotypical development.

Romila Santra, Carolina Pacheco, Deana Crocetti, René Vidal, Stewart H Mostofsky, Bahar Tunçgenç

Abstract read
In one paragraph

Article in The British journal of psychiatry : the journal of mental science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Romila SantraCenter for Neurodevelopmental and Imaging Research, Kennedy Krieger Institute, Baltimore, Maryland, USA.
Carolina PachecoMathematical Institute for Data Science, Johns Hopkins University, Maryland, USA; and Department of Biomedical Engineering, Johns Hopkins University, Maryland, USA.
Deana CrocettiCenter for Neurodevelopmental and Imaging Research, Kennedy Krieger Institute, Baltimore, Maryland, USA.
René VidalSchool of Engineering and Applied Science, University of Pennsylvania, Pennsylvania, USA; and Perelman School of Medicine, University of Pennsylvania, Pennsylvania, USA.
Stewart H MostofskyCenter for Neurodevelopmental and Imaging Research, Kennedy Krieger Institute, Baltimore, Maryland, USA; Department of Neurology, Johns Hopkins University School of Medicine, Maryland, USA; and Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Maryland, USA.
Bahar TunçgençDepartment of Psychology, Nottingham Trent University, UK; and Institute of Human Sciences, University of Oxford, UK.ORCID https://orcid.org/0000-0002-1135-1004

Funding

Sleep and Circadian Dysfunction, Brain and Neurobehavioral Development in AutismP50HD103538 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI S. Ali Fatemi, Bradley L Schlaggar · 2020 to 2026
$9.9M
Somatosensory Inhibitory Dysfunction in Autism Spectrum Disorder.R01MH106564 · NIMH · JOHNS HOPKINS UNIVERSITY · PI EDDEN, RICHARD ANTHONY EDWARD · 2016 to 2020
$2.5M
Illuminating brain function during imitation in children with ASD with DOTR21MH127501 · NIMH · WASHINGTON UNIVERSITY · PI EGGEBRECHT, ADAM THOMAS · 2022 to 2023
$453k
Ultra high-field (7T) in-vivo imaging for detailed characterization of cerebellar dentate nucleus structure and function in children with autismR21MH133012 · NIMH · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI MOSTOFSKY, STEWART H · 2024 to 2025
$417k
National Science Foundation 2124276National Science Foundation 2124277NICHD NIH HHS P50 HD103538NIH HHS MH127501NIH HHS P50 HD103538NIH HHS R01 MH106564NIMH NIH HHS R01 MH106564NIMH NIH HHS R21 MH127501NIMH NIH HHS R21 MH133012Simons Foundation Autism Research Initiative 724867
6 · The paper itself

Abstract

backgroundReliable and specific biomarkers that can distinguish autism spectrum disorders (ASDs) from commonly co-occurring attention-deficit/hyperactivity disorder (ADHD) are lacking, causing misses and delays in diagnosis, and reducing access to interventions and quality of life.

aimsTo examine whether an innovative, brief (1-min), videogame method called Computerised Assessment of Motor Imitation (CAMI), can identify ASD-specific imitation differences compared with neurotypical children and children with ADHD.

methodThis cross-sectional study used CAMI alongside standardised parent-report (Social Responsiveness Scale, Second Edition) and observational measures of autism (Autism Diagnostic Observation Schedule-Second Edition; ADOS-2), ADHD (Conners) and motor ability (Physical and Neurological Examination for Soft Signs). The sample comprised 183 children aged 7-13 years, with ADHD (without ASD), with ASD (with and without ADHD) and who were neurotypical.

resultsRegardless of co-occurring ADHD, children with ASD showed poorer CAMI performance than neurotypical children (

conclusionsFour levels of analyses confirm that poor imitation measured by the low-cost and scalable CAMI method specifically distinguishes ASD not only from neurotypical development, but also from commonly co-occurring ADHD.

Indexed as

Attention Deficit Disorder with HyperactivityAutism Spectrum DisorderDiagnosis, Computer-AssistedImitative BehaviorAdolescentChildCross-Sectional StudiesFemaleHumansMaleattention-deficit hyperactivity disordersAutism spectrum disordersdiagnostic medicineneurodevelopmental disorderssocial functioning

Identifiers

PMID39871516
PMCPMC12301495

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.