Evidence map›Paper›PMID 39871347›Full record

ArticleCritical care (London, England)2025

Solid-state esophageal pressure sensor for the estimation of pleural pressure: a bench and first-in-human validation study.

Julien P van Oosten, Nico Goedendorp, Amne Mousa, Rutger C Flink, Rik Schaart, Merel Flinsenberg, Peter Somhorst, Diederik A M P J Gommers, Leo Heunks, Annemijn H Jonkman

Registry-linked trialAbstract readComparative StudyValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Critical care (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05817968 (Comparison of a Solid State Versus Balloon Esophageal Catheter for Estimation of Pleural Pressure in Surgical ICU Patients), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05817968 nacompletednot on this map

Comparison of a Solid State Versus Balloon Esophageal Catheter for Estimation of Pleural Pressure in Surgical ICU Patients

TypeinterventionalSponsorErasmus Medical CenterRan2023 to 2024Enrolled16ConditionsRespiratory Failure, Mechanical VentilationArmsintelligent Esophageal Pressure Catheter (iEPC)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Julien P van OostenIntensive Care, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands. j.vanoosten@erasmusmc.nl.
Nico GoedendorpIntensive Care, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.
Amne MousaIntensive Care, Amsterdam UMC Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Rutger C FlinkPulmotech B.V, Leek, The Netherlands.
Rik SchaartPulmotech B.V, Leek, The Netherlands.
Merel FlinsenbergIntensive Care, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.
Peter SomhorstIntensive Care, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.
Diederik A M P J GommersIntensive Care, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.
Leo HeunksIntensive Care, Radboud University Medical Center, Nijmegen, The Netherlands.
Annemijn H JonkmanIntensive Care, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdvanced respiratory monitoring through the measurement of esophageal pressure (Pes) as a surrogate of pleural pressure helps guiding mechanical ventilation in ICU patients. Pes measurement with an esophageal balloon catheter, the current clinical reference standard, needs complex calibrations and a multitude of factors influence its reliability. Solid-state pressure sensors might be able to overcome these limitations.

objectivesTo evaluate the accuracy of a new solid-state Pes transducer (Pes

methodsAbsolute and relative solid-state sensor Pes measurements were compared to a reference pressure in a 5-day bench setup, and to simultaneously placed balloon catheters in 15 spontaneously breathing healthy volunteers and in 16 mechanically ventilated ICU patients. Bland-Altman analysis was performed using mixed effects modelling with bootstrapping to estimate bias and upper and lower limits of agreement (LoA) and their confidence intervals.

resultsBench study: Solid-state pressure transducers had a positive bias (P

conclusionsThe novel solid-state pressure transducer showed good accuracy on the bench, in healthy volunteers and in ventilated ICU-patients. This could contribute to the implementation of Pes as advanced respiratory monitoring technique.

trial registrationClinicaltrials.gov identifier: NCT05817968 (patient study). Registered on 18 April 2023.

Indexed as

EsophagusAdultAgedFemaleHumansIntensive Care UnitsMaleMiddle AgedMonitoring, PhysiologicPressureReproducibility of ResultsRespiration, ArtificialTransducers, PressureEsophageal catheterMechanical ventilationPleural pressureRespiratory monitoringSolid-state sensor

Identifiers

PMID39871347
PMCPMC11773869

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.