Evidence map›Paper›PMID 39871334›Full record

ArticleBMC nursing2025

Multiple Sclerosis Nursing to Improve Care and Education (MSNICE): an observational study.

Liesbeth Van Hijfte, Melissa Cambron, Roel Crols, Gino De La Meilleure, Nelly Govers, Ludo Vanopdenbosch, Guy Laureys, Barbara Willekens, MSNICE Study Group

Abstract read
In one paragraph

Article in BMC nursing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Liesbeth Van HijfteDepartment of Neurology, Ghent University Hospital, Ghent, Belgium. liesbeth.vanhijfte@ugent.be.
Melissa CambronDepartment of Neurology, AZ Sint-Jan Brugge, Bruges, Belgium.
Roel CrolsDepartment of Neurology, ZNA Middelheim, Antwerp, Belgium.
Gino De La MeilleureDepartment of Neurology, VITAZ, Sint-Niklaas, Belgium.
Nelly GoversDepartment of Neurology, AZ Sint-Maarten, Mechelen, Belgium.
Ludo VanopdenboschDepartment of Neurology, AZ Sint-Jan Brugge, Bruges, Belgium.
Guy Laureys *Department of Neurology, Ghent University Hospital, Ghent, Belgium.
Barbara Willekens *Faculty of Medicine and Health Sciences, Translational Neurosciences Research GroupTranslational Neurosciences Research Group, Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
MSNICE Study Group

Funding

Koning Boudewijnstichting, ING Mecenaatsfonds 2013-J5930292-200819
6 · The paper itself

Abstract

objectiveTo explore differences in patient reported outcomes, health care resources and expenditures in persons with multiple sclerosis (pwMS) with or without access to an MS-nurse. METHODOLOGY: An observational, multicenter and cross-sectional study was conducted. Seven centers with, and twelve centers without an MS-nurse participated. The multiple sclerosis impact scale-29 (MSIS-29) was the primary outcome measure. Secondary outcome measures included: hospital anxiety and depression scale, coping measures, health-economic and disease-knowledge parameters.

resultsThree hundred thirty-four pwMS were included, of which 196 had access to an MS-nurse. Mean age was 44.5 ± 11.4 and 69% were women. The median expanded disability status scale and patient determined disease steps were respectively 2.0 (IQR 2.5) and 2.5 (IQR 3). No statistical significant differences between centers with or without an MS-nurse were observed for the MSIS-29 (total) (mean ranks: 169.9 vs. 157.8; Z = -1.114; p = .253), depression (X²= 1,772, p = .412), anxiety (X²= 0.446, p = .800) or health expenditures. MS-disease knowledge was higher in patients followed in centers with an MS-nurse than in centers without (17.08(3.37) vs. 15.30(3.39), t(331) = 4.734, p < .001).

conclusionWe did not observe clinical differences regarding HRQoL in pwMS between centers with and without an MS-nurse. Yet, we did observe a higher level of MS-specific knowledge in pwMS who had access to an MS-nurse, which may emphasize the important role of MS-nurses in educating and improving self-efficacy and adherence. Belgian registration number B300201421282.

Indexed as

Health related quality of lifeMultiple sclerosisNurse specialistsNursing economics

Identifiers

PMID39871334
PMCPMC11770908

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.