Evidence map›Paper›PMID 39871298›Full record

ArticleBMC research notes2025

Pattern of antibiotic dispensing at pharmacies according to access, watch, reserve (AWaRe) classification: multicenter study after COVID-19 waves in different districts of Pakistan.

Faiz Ullah Khan, Farman Ullah Khan, Aqsa Sajjad, Tawseef Ahmad, Tauqeer Hussain Mallhi, Sayyad Ali, Kamran Hidayat Ullah, Shahid Shah

Abstract readMulticenter Study
In one paragraph

Article in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Faiz Ullah KhanDepartment of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China. fkhan@bs.qau.edu.pk.
Farman Ullah KhanDepartment of Pharmacy Administration and Clinical Pharmacy, School of Pharmacy, Xi'an Jiaotong University, Xi'an, 710061, China.
Aqsa SajjadDepartment of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Government College University Faisalabad, Faisalabad, 37000, Pakistan.
Tawseef AhmadDepartment of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat-Yai, 90110, Thailand. tausifsafi95@gmail.com.
Tauqeer Hussain MallhiDepartment of Clinical Pharmacy, College of Pharmacy, Al-Jouf Province, Jouf University, Sakaka, Kingdom of Saudi Arabia.
Sayyad AliMuhammad Islam College of Pharmacy, Gujranwala, 52280, Pakistan.
Kamran Hidayat UllahDepartment of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China.
Shahid ShahDepartment of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Government College University Faisalabad, Faisalabad, 37000, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe dispensing of non-prescription antibiotics is a worldwide concern, and antibiotics should only be dispensed with a legitimate prescription. METHODOLOGY: A cross-sectional study was conducted using the simulated client methodology, with data collected, recorded, and analyzed using SPSS.

resultsThe simulated client visited 210 pharmacies, of which 70 dispensed antibiotics without a prescription. Outcomes The most often suggested antibiotics for upper respiratory tract infections (URTIs) were Amoxicillin (n = 17, 8.1%), Clarithromycin (n = 20, 9.5%), and Moxifloxacin (n = 13, 6.2%), with 33.3% of medications dispensed without a prescription for URTIs. Cefixime (n = 20, 9.5%) and ceftriaxone (n = 17, 8.1%) were the most often administered medications for urinary tract infections (UTIs). The non-prescribed dispensing of upper respiratory tract infections (URTIs) and urinary tract infections (UTIs) was markedly elevated (p < 0.05). Antibiotics were dispensed without a prescription for diarrheal diseases in over 50% of pharmacies, with Metronidazole (n = 23, 11%), Azithromycin (n = 16, 7.6%), and Rifaximin (n = 15, 7.1%) being the most often prescribed. In all bivariate and multivariate models, male gender was associated with reduced likelihood (COR: 0.30, 95% CI: 0.12-0.72; p = 0.0079 and AOR: 0.03, 95% CI: 0.005-0.15; p = 0.0001). Individuals aged 30 years and older exhibited increased odds of dispensing in both bivariate (COR: 3.67, 95% CI: 1.69-8.87; p = 0.0018) and multivariate analyses (AOR: 9.44, 95% CI: 2.55-61.70; p = 0.001). The presence of a pharmacist on duty markedly diminished the likelihood of administering antibiotics without a prescription (COR: 0.13, 95% CI: 0.06-0.25; p = < 0.001; AOR: 0.06, 95% CI: 0.03-0.16; p = < 0.001).

conclusionThese findings highlight the imperative of enforcing existing laws and implementing rigorous rules, alongside pharmacy-centered antimicrobial stewardship programs that focus on accurate dispensing practices to mitigate antimicrobial resistance.

Indexed as

Anti-Bacterial AgentsCOVID-19Drug PrescriptionsPharmaciesPractice Patterns, Pharmacists'AdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedPakistanRespiratory Tract InfectionsSARS-CoV-2Urinary Tract InfectionsAnti-Bacterial AgentsAntibioticsAWaRe classificationDiarrheal infectionsPharmacyUpper respiratory tract infectionUrinary tract infectionWithout prescription antibiotics dispensing

Identifiers

PMID39871298
PMCPMC11773753

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.