ArticleBMC musculoskeletal disorders2025
Risk factors for growth retardation in children with juvenile idiopathic arthritis: a case-control study.
Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Prednisone, not vamorolone, suppresses novel serum bone and cartilage biomarkers associated with growth failure in children with Duchenne muscular dystrophy.Scientific reports · 2026Trial
- Post-Marketing Safety Surveillance of Autoimmune Diseases Following Bivalent Human Papillomavirus Vaccination in China.Vaccines · 2026Article
- Clinical biochemical evaluation of trace elements and insulin-like growth factor-I in children with short stature: Diagnostic and correlative insights from the Guangzhou cohort.Journal of medical biochemistry · 2026Article
- Facial Proportions in Stunted and Non-Stunted Children Aged 7-72 Months: A Cross-Sectional Study in Bandung, Indonesia.Children (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
objectiveThis study aimed to investigate the role of various factors contributing to growth retardation, including nutritional intake, disease duration, and treatment history, and further identify key risk factors that may influence growth outcomes in patients with juvenile idiopathic arthritis (JIA).
methodsClinical data from 155 JIA children who were treated at our hospital between January 2019 and December 2022 were analyzed. The children were divided into the growth retardation group (n = 40) and the non-growth retardation group (n = 115) based on the height Z-score < -2 SD or not. The two groups were compared based on their baseline characteristics, disease-related factors, dietary habits, lifestyle, and family background. Logistic regression and receiver operating characteristic (ROC) curve analyses were employed to identify and assess the factors associated with growth retardation.
resultsOut of the 155 children, 40 (25.81%) were diagnosed with growth retardation. Children with growth retardation were more likely to have a disease duration ≥ 3 years (72.50% vs. 39.13%, P < 0.001), exercise time < 1 h/per day (68.50% vs. 33.04%, P < 0.001), glucocorticoid use (65.00% vs. 34.78%, P = 0.001), and active disease activity (72.50% vs. 37.39%, P < 0.001). These factors were identified as independent risk factors for growth retardation in multivariate analysis. The area under the curve (AUC) values for these factors ranged from 0.651 to 0.676, indicating moderate predictive accuracy. When considering all these factors together, the combined model demonstrated an AUC value of 0.702, suggesting a high predictive value.
conclusionThe incidence of growth retardation in children with JIA is high, with factors such as disease duration, exercise time, GC treatment, clinic visits, picky eating, and disease activity contributing to its development. While each of these factors demonstrates moderate predictive value individually, their combined consideration significantly improves predictive accuracy. CLINICAL TRIAL NUMBER: Not applicable.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.