Observational studyHealth and quality of life outcomes2025
Relationship between social support, functional outcomes and health-related quality of life in working-aged adults at three months after ischemic stroke: results from the FRAILTY study.
Observational study in Health and quality of life outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04839887 (Factors Affecting the Quality of Life After Ischemic Stroke in Young Adults), which is not on this map. Cited by 10 papers.
What it found
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The trial behind it
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Factors Affecting the Quality of Life After Ischemic Stroke in Young Adults: a Prospective Observational Study in Young Ischemic Stroke Patients Under 50 Years
Who cites it
10 citing papers in PubMed.
- Current Progress of Mechanisms Underlying Post-Stroke Depression and Music Therapy.Chinese journal of integrative medicine · 2026Review
- The association of social isolation and family structure on stroke-specific quality of life in a community-based study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Predictive factors for remission in post-stroke depression: A Markov model cohort study.iScience · 2026Article
- Prediction model for frailty risk in ischemic stroke patients: Application and validation of support vector machines and nomograms.Medicine · 2026Article
- Trajectories and Influencing Factors of Depression in Patients with H-Type Hypertension-Related Ischemic Stroke: A Single-Center Longitudinal Study.Patient preference and adherence · 2026Article
- The association between social support and quality of life in patients with severe stroke: a chain mediation analysis of resilience and self-efficacy.Frontiers in psychiatry · 2026Article
- Article
- Inequities in Stroke Recovery: Examining Sociodemographic Predictors of Rehabilitation Success.Healthcare (Basel, Switzerland) · 2025Article
- Association between social participation and hope levels in stroke patients: a cross-sectional study.Frontiers in psychology · 2025Article
- Experiences of Young and Middle-Aged Stroke Patients with Hemiplegia Who Actively Participate in Rehabilitation Exercises and Their Perceptions of Well-Being: A Descriptive Qualitative Study.Risk management and healthcare policy · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe relationship between social support and functional outcomes and health-related quality of life (HRQoL) after ischemic stroke (IS) remains unclear, especially in working-aged patients.
aimTo assess the relationship between perceived social support, functional outcomes, post-stroke psychosocial symptoms, and HRQoL in working-aged adults three months after IS.
methodsA prospective and correlational design was used. Patients of working age (18-65 years) admitted for first-ever IS were enrolled in the prospective FRAILTY (Factors Affecting the Quality of Life After Ischemic Stroke in Young Adults) study (NCT04839887). HRQoL (using the Stroke Impact Scale, Quality of Life in Neurological Disorders), social support (using the Multidimensional Scale of Perceived Social Support), functional outcomes (using a modified Rankin Scale-mRS), and post-stroke psychosocial symptoms were assessed three months after IS. Descriptive statistics, Wilcoxon signed-rank test, Spearman's correlations and multiple linear regression were used for analysis.
resultsA total of 121 (54.5% males, mean age 51.7 ± 8.4 years) IS patients were analyzed. Of those, 87.7% had excellent clinical outcomes (mRS 0-1) after three months. Patients reported significant improvement in all domains of self-reported HRQoL except memory and communication after three months. The overall perceived social support was not associated with HRQoL domains. Post-stroke depression was negatively associated with all domains of HRQoL. Living arrangements (living alone) and post-stroke depression were negatively associated with perceived social support after IS.
conclusionsMore insight into the relationship between variables of HRQoL in working-aged adults might increase their social participation, strengthen supportive relationships, and promote their recovery and rehabilitation process. Focusing on the management of emotional problems and supporting functional outcomes may be modifiable factors that may represent targets for strategies to improve the HRQoL. Further research is needed to clarify the relationship between pre-stroke perceived social support and its types and post-stroke psychosocial symptoms in the long term.
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