Evidence map›Paper›PMID 39871067›Full record

GuidelineJournal of assisted reproduction and genetics2025

Prenatal diagnosis following preimplantation genetic testing (PGT): recommendations of the Italian Society of Human Genetics (SIGU).

Francesca Romana Grati, Antonio Capalbo, Ilaria Gabbiato, Paola Battaglia, Maria Carla Pittalis, Domenico Bizzoco, Laura Cardarelli, Valentina Gatta, Fortunato Lonardo, Antonio Novelli and 3 more

Abstract readPractice Guideline
In one paragraph

Guideline in Journal of assisted reproduction and genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Francesca Romana Grati *Reproductive Precision Medicine Unit, Menarini Silicon Biosystems, Castel Maggiore, Bologna, Italy.ORCID http://orcid.org/0000-0002-3836-5190
Antonio Capalbo *Unità Di Genetica Medica, CAST, Università "G. d'Annunzio" Chieti-Pescara, Chieti, Italy.ORCID http://orcid.org/0000-0003-0109-323X
Ilaria GabbiatoMedical Genetics & Genomics Unit, AULSS8 Berica, Vicenza, Italy.
Paola BattagliaMedical Genetics Unit, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.
Maria Carla PittalisMedical Genetics Unit, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy.
Domenico BizzocoLaboratorio Di Genetica MEDIGENE, Rome, Italy.
Laura CardarelliRDI - Gruppo Cerba HealthCare Italia, Limena, Padua, Italy.
Valentina GattaUnità Di Genetica Medica, CAST, Università "G. d'Annunzio" Chieti-Pescara, Chieti, Italy.
Fortunato LonardoU.O.S.D. di Genetica Medica, A.O.R.N San Pio, Benevento, Italy.ORCID http://orcid.org/0000-0002-5712-0754
Antonio NovelliU.O.C. Laboratorio Di Genetica Medica, Ospedale Bambino Gesù, IRCCS, Rome, Italy.
Laura BernardiniMedical Genetics Division, San Giovanni Rotondo, Casa Sollievo della Sofferenza Foundation, Foggia, FG, Italy. l.bernardini@css-mendel.it.ORCID http://orcid.org/0000-0002-3554-2817
Daniela ZuccarelloMedical Genetics & Genomics Unit, AULSS8 Berica, Vicenza, Italy.ORCID http://orcid.org/0000-0001-5826-6715
Italian Society of Human Genetics (SIGU)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This document aims to provide good practice recommendations in order to support maternal-foetal medicine specialists, clinical geneticists and clinical laboratory geneticists in the management of pregnancies obtained after the transfer of an embryo tested with preimplantation genetic testing (PGT). It was drafted by geneticists expert in preimplantation genetics and prenatal genetic diagnosis belonging to the "Working Group in Cytogenomics, Prenatal and Reproductive Genetics" of the "Italian Society of Human Genetics" (SIGU). In particular, the paper addresses the diagnostic algorithm to be applied in prenatal follow-up depending on the type of PGT performed, the results obtained and the related diagnostic value based on the most recent literature data and Italian and international recommendations.

Indexed as

Genetic TestingPreimplantation DiagnosisPrenatal DiagnosisEmbryo TransferFemaleFertilization in VitroHumansItalyPregnancySocieties, MedicalEmbryoMosaicismPGT-APGT-MPGT-SRPrenatal diagnosis

Identifiers

PMID39871067
PMCPMC11950599

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.