Evidence map›Paper›PMID 39871027›Full record

ArticleJournal of cancer survivorship : research and practice2026

Fear of cancer recurrence in long-term colorectal cancer survivors: a nationwide cross-sectional study.

Johanne Dam Lyhne, Lars Henrik Jensen, Per Fink, Signe Timm, Lisbeth Frostholm, Allan 'Ben' Smith

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cancer survivorship : research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. How prevalent is fear of cancer recurrence beyond 5 years: a systematic review of validated assessments across tumour types.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
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  5. Network temperature and stability of symptom clusters in colorectal cancer patients undergoing adjuvant chemotherapy: a prospective longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Johanne Dam LyhneDepartment of Oncology, Lillebaelt Hospital - Vejle, University Hospital of Southern Denmark, Beriderbakken 4, 7100, Vejle, Denmark. Johanne.Dam.Lyhne@rsyd.dk.
Lars Henrik JensenDepartment of Oncology, Lillebaelt Hospital - Vejle, University Hospital of Southern Denmark, Beriderbakken 4, 7100, Vejle, Denmark.
Per FinkDepartment for Functional Disorders, Aarhus University Hospital, Palle Juul-Jensens, Boulevard 11, Indgang A, Plan 9, A903, 8200, Aarhus N, Denmark.
Signe TimmDepartment of Oncology, Lillebaelt Hospital - Vejle, University Hospital of Southern Denmark, Beriderbakken 4, 7100, Vejle, Denmark.
Lisbeth FrostholmDepartment for Functional Disorders, Aarhus University Hospital, Palle Juul-Jensens, Boulevard 11, Indgang A, Plan 9, A903, 8200, Aarhus N, Denmark.
Allan 'Ben' SmithThe Daffodil Centre, The University of Sydney, A Joint Venture With Cancer Council NSW, 153 Dowling St, Woolloomooloo, Sydney, NSW, 2011, Australia.

Funding

Kræftens Bekæmpelse 17152
6 · The paper itself

Abstract

purposeKnowledge about fear of cancer recurrence (FCR) among recurrence-free long-term colorectal cancer survivors (CRCS) is limited. This national cross-sectional study aimed to (1) assess the prevalence and correlates of FCR among CRCS; (2) investigate associations between colorectal cancer-specific symptoms and FCR; and (3) identify predictors of interest in engaging in FCR treatment.

methodsWe identified 9638 living Danish CRCS, age above 18 years, diagnosed between 2014 and 2018 through the Danish Clinical Registries. Electronic surveys were distributed between May 2023 and May 2024. FCR was measured on the Fear of Cancer Recurrence Inventory - Short Form (FCRI-SF). Associations with colorectal cancer-specific physical symptoms and psychological symptoms were analyzed using logistic regression models.

resultsOf 5480 respondents (56.9%; mean age: 73, range (30-99; 42% female), 5.3% of survivors reported clinical FCR (cFCR). In multivariate analyses, having severe abdominal pain (OR 8.7 (95% CI 4.8-15.8)), abdominal bloating, tension, or heaviness (OR 10.0 (95% CI (6.1-16.3)) and tiredness (OR 7.1 (95% CI (4.1-12.1)) were associated with increased odds of cFCR, as were psychological symptoms (health anxiety; OR 19.7 (95% CI (13.5-28.6)), anxiety; OR 11.2 (95% CI (6.4-19.6)), depression; OR 5.5 (95% CI (2.6-11.9)) compared to no FCR. Among those with cFCR, 75% were interested in treatment, with higher interest among males and chemotherapy recipients.

conclusionFCR severity is strongly associated with specific colorectal symptoms, tiredness, and psychological symptoms. IMPLICATIONS FOR CANCER SURVIVORS: Addressing cancer-specific physical symptoms may be a promising strategy for reducing FCR.

Indexed as

Cancer SurvivorsColorectal NeoplasmsFearNeoplasm Recurrence, LocalAdultAgedAged, 80 and overCross-Sectional StudiesDenmarkFemaleHumansMaleMiddle AgedColorectal cancerHealth anxietyLate effectsOdds ratioPatient-reported outcome measuresSurvivorship

Identifiers

PMID39871027
PMCPMC13375672

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.