Evidence map›Paper›PMID 39870987›Full record

ArticleMedical & biological engineering & computing2025

State-dependent neurovascular modulation induced by transcranial ultrasound stimulation.

Hang Song, Ruoyu Chen, Liyuan Ren, Junfeng Sun, Shanbao Tong

Abstract read
PubMed Publisher
In one paragraph

Article in Medical & biological engineering & computing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hang SongSchool of Biomedical Engineering, Shanghai Jiao Tong University, No.1954 Huashan Road, Shanghai, 200030, Shanghai, China.
Ruoyu ChenSchool of Biomedical Engineering, Shanghai Jiao Tong University, No.1954 Huashan Road, Shanghai, 200030, Shanghai, China.
Liyuan RenSchool of Biomedical Engineering, Shanghai Jiao Tong University, No.1954 Huashan Road, Shanghai, 200030, Shanghai, China.
Junfeng SunSchool of Biomedical Engineering, Shanghai Jiao Tong University, No.1954 Huashan Road, Shanghai, 200030, Shanghai, China. jfsun@sjtu.edu.cn.ORCID http://orcid.org/0000-0002-7614-7127
Shanbao TongSchool of Biomedical Engineering, Shanghai Jiao Tong University, No.1954 Huashan Road, Shanghai, 200030, Shanghai, China. stong@sjtu.edu.cn.

Funding

National Key R&D Program of China 2022YFC3601200National Natural Science Foundation of China 61876108National Natural Science Foundation of China 62376157National Natural Science Foundation of China 82472097Science and Technology Major Project of Inner Mongolia 2022XYJG0001-01-21the MOST 2030 Brain Project 2022ZD0208500
6 · The paper itself

Abstract

Previous studies reported baseline state-dependent effects on neural and hemodynamic responses to transcranial ultrasound stimulation. However, due to neurovascular coupling, neither neural nor hemodynamic baseline alone can fully explain the ultrasound-induced responses. In this study, using a general linear model, we aimed to investigate the roles of both neural and hemodynamic baseline status as well as their interactions in ultrasound-induced responses. Thirty Sprague-Dawley rats were randomly assigned to Hypoxia, Hyperoxia, and Normoxia groups. The baseline states were altered by changing the oxygen concentrations. Micro-electrode and laser speckle contrast imaging were used to record local field potentials and cerebral blood flow during resting, before, and after ultrasound stimulation, respectively. We found that baseline neural activity played a positive role in neural response (Coefficient = 0.634, t = 1.748, p = 0.096,

Indexed as

Cerebrovascular CirculationNeurovascular CouplingUltrasonic WavesAnimalsBrainHemodynamicsHyperoxiaHypoxiaMaleRatsRats, Sprague-DawleyUltrasonography, Doppler, TranscranialGeneral linear modelNeurovascular couplingState-dependent effectTranscranial ultrasound stimulation

Identifiers

PMID39870987

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.