Evidence map›Paper›PMID 39870981›Full record

ArticleClinical and experimental nephrology2025

Exploring factors associated with Kidney Disease Quality of Life in patients with advanced chronic kidney disease: the Reach-J CKD cohort study.

Hironori Nakamura, Reiko Okubo, Michiko Kumagai, Mariko Anayama, Yasushi Makino, Katsuhiko Tamura, Masaki Nagasawa, Hirokazu Okada, Shoichi Maruyama, Junichi Hoshino and 3 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Clinical and experimental nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hironori NakamuraDepartment of Nephrology, Shinonoi General Hospital, 666-1 Ai Shinonoi, Nagano, 388-8004, Japan. hnakamur0525@gmail.com.ORCID http://orcid.org/0000-0003-0066-8070
Reiko OkuboDepartment of Health Care Policy and Health Economics, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Michiko KumagaiDepartment of Nephrology, Shinonoi General Hospital, 666-1 Ai Shinonoi, Nagano, 388-8004, Japan.
Mariko AnayamaDepartment of Nephrology, Shinonoi General Hospital, 666-1 Ai Shinonoi, Nagano, 388-8004, Japan.
Yasushi MakinoDepartment of Nephrology, Shinonoi General Hospital, 666-1 Ai Shinonoi, Nagano, 388-8004, Japan.
Katsuhiko TamuraDepartment of Nephrology, Shinonoi General Hospital, 666-1 Ai Shinonoi, Nagano, 388-8004, Japan.
Masaki NagasawaDepartment of Nephrology, Shinonoi General Hospital, 666-1 Ai Shinonoi, Nagano, 388-8004, Japan.
Hirokazu OkadaReach-J Steering Committee, Tsukuba, Ibaraki, Japan.
Shoichi MaruyamaReach-J Steering Committee, Tsukuba, Ibaraki, Japan.
Junichi HoshinoReach-J Steering Committee, Tsukuba, Ibaraki, Japan.
Takashi WadaReach-J Steering Committee, Tsukuba, Ibaraki, Japan.
Ichiei NaritaReach-J Steering Committee, Tsukuba, Ibaraki, Japan.
Kunihiro YamagataReach-J Steering Committee, Tsukuba, Ibaraki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough several studies have examined the Kidney Disease Quality of Life (KDQOL) in patients with chronic kidney disease (CKD), the factors associated with kidney-related symptoms have not been fully explored.

methodsThis nationwide multicenter cohort study enrolled 2248 patients. To identify the factors associated with each item or the three KDQOL domains, such as burden of kidney disease, symptoms/problems of kidney disease, and impact of kidney disease on daily life, multiple regression analysis was performed using baseline data.

resultsThe study population had a mean age of 69.1 ± 12.6 years, comprised 64.7% men, and had mean estimated glomerular filtration rate (eGFR) of 23.2 ± 10.4 mL/min/1.73 m

conclusionsIn addition to eGFR, several factors were associated with symptoms in patients with CKD. Nephrologists need to recognize renal dysfunction-specific symptoms and explore other plausible causes of nonspecific symptoms.

Indexed as

KidneyQuality of LifeRenal Insufficiency, ChronicAgedAged, 80 and overCohort StudiesFemaleGlomerular Filtration RateHumansMaleMiddle AgedAdvanced CKDAgingeGFRKDQOLSymptom

Identifiers

PMID39870981

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.