Evidence map›Paper›PMID 39870977›Full record

ReviewNature reviews. Molecular cell biology2025

The roles of mitochondria in global and local intracellular calcium signalling.

Benjamín Cartes-Saavedra, Arijita Ghosh, György Hajnóczky

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Molecular cell biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Mitochondrial CaAntioxidants (Basel, Switzerland) · 2026
    Article
  9. Hypertensive mt. tRNARedox biology · 2026
    Article
  10. Article
  11. Asymmetric distribution of mitochondrial CaExperimental & molecular medicine · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Ryanodine Receptor CaActa physiologica (Oxford, England) · 2026
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Benjamín Cartes-Saavedra *MitoCare Center, Department of Pathology and Genomic Medicine, Thomas Jefferson University, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-2753-5780
Arijita Ghosh *MitoCare Center, Department of Pathology and Genomic Medicine, Thomas Jefferson University, Philadelphia, PA, USA.ORCID https://orcid.org/0000-0002-6277-1746
György HajnóczkyMitoCare Center, Department of Pathology and Genomic Medicine, Thomas Jefferson University, Philadelphia, PA, USA. gyorgy.hajnoczky@jefferson.edu.ORCID http://orcid.org/0000-0003-3813-2570

Funding

ER-mitochondrial communication in calcium signaling, energy metabolism and liver diseaseR01DK125897 · NIDDK · THOMAS JEFFERSON UNIVERSITY · PI CSORDAS, GYORGY, HAJNOCZKY, GYORGY · 2021 to 2025
$2.7M
Developing tools for calcium imaging in ITPR2-linked liver pathogenesisR03TR004644 · NCATS · THOMAS JEFFERSON UNIVERSITY · PI HAJNOCZKY, GYORGY · 2023 to 2023
$156k
NCATS NIH HHS R03 TR004644NIDDK NIH HHS R01 DK125897
6 · The paper itself

Abstract

Activation of Ca

Indexed as

CalciumCalcium SignalingMitochondriaAnimalsCalcium ChannelsCytoplasmHumansCalciumCalcium Channels

Identifiers

PMID39870977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.