ReviewNature reviews. Gastroenterology & hepatology2025
Rome Foundation Working Team Report on overlap in disorders of gut-brain interaction.
Review in Nature reviews. Gastroenterology & hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Physical-based therapy for the treatment of functional dyspepsia: a systematic review.Clinical journal of gastroenterology · 2026Pooled it
- Wearable-Based Monitoring of Autonomic and Gastrointestinal Function in Disorders of Gut-Brain Interaction: A Systematic Review and Meta-Analyses.Neurogastroenterology and motility · 2026Pooled it
- Life-course hygiene exposures and disorders of gut-brain interaction: a multinational cross-sectional study.Internal and emergency medicine · 2026Article
- Irritable bowel syndrome.Nature reviews. Disease primers · 2026Review
- Article
- Prevalence and Burden of Fatigue Across Disorders of Gut-Brain Interaction: Results From the Rome Foundation Global Epidemiology Study.Alimentary pharmacology & therapeutics · 2026Article
- Distinct pain profiles across irritable bowel syndrome subtypes: results from the Rome Foundation Global Epidemiology Study.Internal and emergency medicine · 2026Article
- Preliminary Investigation of Disorders of Gut-Brain Interaction and Their Associations With Psychological Flexibility and Daily Functioning in People With Fibromyalgia.European journal of pain (London, England) · 2026Article
- Burden, features and factor associated with disorders of gut-brain axis in Italy: results from the Rome foundation global epidemiology study.Internal and emergency medicine · 2026Article
- Managing the Diagnostic and Therapeutic Challenges of Irritable Bowel Syndrome.Gastroenterology & hepatology · 2026Article
- Prevalence of Self-Reported Non-Coeliac Gluten Sensitivity and Its Association With Disorders of Gut-Brain Interaction and Disordered Eating.United European gastroenterology journal · 2026Article
- Comparative Study on Burden, Features and Determinants of Disorders of Gut-Brain Interaction Between Southern Europe and the Rest of Continent: Results From the Rome Foundation Global Epidemiology Study.United European gastroenterology journal · 2026Article
- Prevalence of disorders of gut-brain-interaction in pediatric patients with in-remission inflammatory bowel disease: An Italian multicenter study.Journal of pediatric gastroenterology and nutrition · 2026Article
- Clinical characteristics and nutritional profiles of children with different irritable bowel syndrome subtypes: a retrospective hospital-based study.Translational pediatrics · 2026Article
- Brain-body interactions in systemic diseases: a survey from an imaging perspective.MedScience · 2026Review
- A Roadmap for Advancing Women's Health in Disorders of the Gut-Brain Interaction.United European gastroenterology journal · 2026Review
- Bloating, Visible Abdominal Distension, and Other Intestinal Gas-Related Symptoms in Irritable Bowel Syndrome and Functional Dyspepsia.United European gastroenterology journal · 2026Article
- Overlap of 'disorders of gut-brain interaction': A type of diseases that require special attention.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- Circadian regulation of gastrointestinal motility and the effect on disorders of gut-brain interaction.Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi · 2026Review
- Pathogenesis and therapeutic strategies for irritable bowel syndrome: an integrated perspective from dynamic balance theory of Chinese medicine.Frontiers in medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In patients with disorders of gut-brain interaction (DGBI), overlapping non-gastrointestinal conditions such as fibromyalgia, headaches, gynaecological and urological conditions, sleep disturbances and fatigue are common, as is overlap among DGBI in different regions of the gastrointestinal tract. These overlaps strongly influence patient management and outcome. Shared pathophysiology could explain this scenario, but details are not fully understood. This overlap has been shown to be of great relevance for DGBI. In addition, symptoms considered to be caused by a DGBI could have a detectable organic cause, and in patients with a diagnosed organic gastrointestinal disease, symptoms not clearly explained by the pathology defining this organic disease are common. Thus, the aims of this Rome Foundation Working Team Report were to review the literature on overlapping conditions among patients with paediatric and adult DGBI and, based on the available epidemiological and clinical evidence, make recommendations for the current diagnostic and therapeutic approach, and for future research. Specifically, we focused on other DGBI in the same or different gastrointestinal anatomical region(s), DGBI overlap with organic bowel diseases in remission, and DGBI overlap with non-gastrointestinal, non-structural conditions.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.