ArticleNPJ digital medicine2025
AI driven decision support reduces antibiotic mismatches and inappropriate use in outpatient urinary tract infections.
Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Artificial Intelligence in Infectious Disease Care: Selected Applications in Tuberculosis, Sepsis, and Antimicrobial Stewardship.Diagnostics (Basel, Switzerland) · 2026Review
- Physician adoption patterns of AI-driven clinical decision support systems in urinary tract infection management.Scientific reports · 2026Article
- Artificial Intelligence in Dialysis Therapies:Saudi medical journal · 2026Review
- Optimizing antimicrobial stewardship in urology: a qualitative study on needs, values and requirements for clinical decision support.Infection prevention in practice · 2026Article
- Integrated iPRISM Direct-on-Urine Platform for Rapid UTI Diagnosis in a Double-Blind Clinical Trial.ACS measurement science au · 2026Article
- The effect of AI-assisted bedside echocardiography on inpatient care: a prospective trial.European heart journal. Digital health · 2026Article
- Algorithmic antibiotic decision-making in urinary tract infection using prescriber-informed prediction of treatment utility.NPJ digital medicine · 2026Article
- Application of artificial intelligence in geriatric infection: recent advances and prospects.Frontiers in cellular and infection microbiology · 2026Review
- From surveillance to intelligence: a scoping review of machine learning for antimicrobial resistance surveillance intelligence across One Health.Frontiers in public health · 2026Article
- Precision diagnosis of preoperative infection in urolithiasis: integrating targeted next-generation sequencing for enhanced accuracy-a multicenter cohort study.BMC infectious diseases · 2025Article
- Machine Learning-Based Prediction of Antimicrobial Susceptibility: A Step Towards Precision Antimicrobial Stewardship.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024Article
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Authors and funding
7 authors.
Funding
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Abstract
Urinary tract infections (UTIs) often prompt empiric outpatient antibiotic prescriptions, risking mismatches. This study evaluates the impact of "UTI Smart-Set" (UTIS), an AI-driven decision-support tool, on prescribing patterns and mismatches in a large outpatient organization. UTIS integrates machine learning forecasts of antibiotic resistance, patient data, and guidelines into a user-friendly order set for UTI management. From 6/1/2021-8/31/2022, 171,010 UTI diagnoses were recorded, with UTIS used in 75,630 cases involving antibiotic prescriptions. Overall acceptance rate of UTIS recommendations was 66.0%. Among 19,287 cases with urine cultures, antibiotic mismatch rate was significantly lower when UTIS recommendations were followed (8.9% vs. 14.2%, p < 0.0001). Among women over 18, mismatch rate was 47.5% lower, and among women over 50, 55.6% lower (p < 0.001). Additionally, an overall reduction of 80.5% in ciprofloxacin usage (6.4% vs 32.9%, p < 0.0001) was observed. UTIS improved prescribing accuracy, reduced mismatches, and minimized quinolone use, highlighting AI's potential for personalized infection management.
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