Evidence map›Paper›PMID 39870845›Full record

Trial reportSkeletal radiology2025

Platelet-rich plasma does not influence magnetic resonance imaging findings of the gluteus muscles after total hip arthroplasty through the Hardinge approach.

Anette Nieminen, Janne Nurminen, Anni Aavikko, Jani Puhakka, Jussi Haapala, Hannes Keemu, Juha Kukkonen, Ari Alho, Panu Uusalo, Keijo Mäkelä and 1 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Skeletal radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

11 authors.

Anette NieminenDepartment of Orthopedics and Traumatology, Turku University Hospital, University of Turku, Luolavuorentie 2, 20700, Turku, Finland. anenie@utu.fi.
Janne NurminenDepartment of Radiology, Turku University Hospital, University of Turku, Turku, Finland.
Anni AavikkoDepartment of Orthopedics and Traumatology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Jani PuhakkaDepartment of Orthopedics and Traumatology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Jussi HaapalaDepartment of Orthopedics and Traumatology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Hannes KeemuDepartment of Orthopedics and Traumatology, Turku University Hospital, University of Turku, Luolavuorentie 2, 20700, Turku, Finland.
Juha KukkonenDepartment of Surgery, Satakunta Central Hospital, Pori, Finland.
Ari AlhoDepartment of Anaesthesiology and Intensive Care, University of Turku, Turku, Finland.
Panu UusaloDepartment of Anaesthesiology and Intensive Care, University of Turku, Turku, Finland.
Keijo MäkeläDepartment of Orthopedics and Traumatology, Turku University Hospital, University of Turku, Luolavuorentie 2, 20700, Turku, Finland.
Jussi KosolaDepartment of Orthopedics and Traumatology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTotal hip arthroplasty through the Hardinge approach damages the hip abductor muscles. MRI can be used to assess adverse postoperative events. In this prospective randomized controlled trial, we evaluated MRI findings and whether platelet-rich plasma affected postoperative healing of the gluteal muscles (gluteus medius and minimus). MATERIALS AND

methodsForty patients with hip osteoarthritis requiring treatment with total hip arthroplasty, aged between 60 and 76 years, were included. Patients were randomized into two groups: 19 patients in the platelet-rich plasma group and 21 in the placebo group. Platelet-rich plasma or placebo was injected into the gluteus medius tendon incision line during closure. Postoperative hip MRI and plain radiographs were taken 3 and 12 months after surgery.

resultsMRI showed fatty atrophy of the gluteal muscles in all 40 patients (100%), gluteal muscle tear in 11 patients (28%), and atrophy in 16 patients (40%) at both 3 and 12 months postoperatively. Fluid collections related to the operated hip joint were seen in 18 patients (45%) at 3 months and 13 patients (33%) at 12 months, heterotopic ossification formation in nine patients (23%) at 3 months, and 12 patients (31%) at 12 months. There were no significant differences in imaging findings between the two groups.

conclusionMRI can be a valuable tool for evaluating postoperative healing after total hip arthroplasty. Fatty atrophy of the gluteal muscles was a common finding. Platelet-rich plasma injection into the gluteus medius tendon did not improve healing detected by MRI.

Indexed as

Arthroplasty, Replacement, HipMagnetic Resonance ImagingMuscle, SkeletalMuscular AtrophyOsteoarthritis, HipPlatelet-Rich PlasmaPostoperative ComplicationsAgedButtocksFemaleHumansMaleMiddle AgedProspective StudiesTreatment OutcomeMRIPlatelet-rich plasmaTotal hip arthroplasty

Identifiers

PMID39870845
PMCPMC12174256

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