Evidence map›Paper›PMID 39870840›Full record

ArticleCardiovascular and interventional radiology2025

Minimally Invasive Treatment of Aneurysmal Bone Cysts with Gelified Ethanol (DiscoGel®): Evaluation of Feasibility, Safety, and Efficacy.

Valentin Gineys, Rémi Grange, Nicolas Stacoffe, Sylvain Bertholon, Hassan Al Khoury Salem, Elie Haddad, Claire Boutet, Sylvain Grange

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Article in Cardiovascular and interventional radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Valentin GineysDepartment of Radiology, University Hospital of Saint Etienne, Avenue Albert Raymond, 42055, Saint-Priest-en-Jarez, Saint-Etienne Cedex 2, France.
Rémi GrangeDepartment of Radiology, University Hospital of Saint Etienne, Avenue Albert Raymond, 42055, Saint-Priest-en-Jarez, Saint-Etienne Cedex 2, France.
Nicolas StacoffeDepartment of Radiology, Groupement Hospitalier Sud, Hospices Civils de Lyon, 69495, Pierre-Bénite, France.
Sylvain BertholonDepartment of Radiology, University Hospital of Saint Etienne, Avenue Albert Raymond, 42055, Saint-Priest-en-Jarez, Saint-Etienne Cedex 2, France.
Hassan Al Khoury SalemDepartment of Pediatric Surgery, University Hospital of Saint Etienne, Avenue Albert Raymond, 42055, Saint-Etienne Cedex 2, France.
Elie HaddadDepartment of Pediatric Surgery, University Hospital of Saint Etienne, Avenue Albert Raymond, 42055, Saint-Etienne Cedex 2, France.
Claire BoutetDepartment of Radiology, University Hospital of Saint Etienne, Avenue Albert Raymond, 42055, Saint-Priest-en-Jarez, Saint-Etienne Cedex 2, France.
Sylvain GrangeDepartment of Radiology, University Hospital of Saint Etienne, Avenue Albert Raymond, 42055, Saint-Priest-en-Jarez, Saint-Etienne Cedex 2, France. sylvain.grange@chu-st-etienne.fr.ORCID http://orcid.org/0000-0003-3706-297X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAneurysmal bone cysts are locally aggressive bone lesions. The aim of this study was to evaluate safety and effectiveness of radio-opaque gelified ethanol sclerotherapy in treating primary aneurysmal bone cyst. MATERIALS AND

methodsIn this single-center, retrospective study (January 1st, 2012, to June 30th, 2024), 32 patients with primary aneurysmal bone cysts were treated with percutaneous sclerotherapy using radio-opaque gelified ethanol at various skeletal sites. Of these, 27 patients were included in the analysis, 5 patients were excluded due to follow-up of less than 12 months. The primary outcome measure was the safety of the procedures. Secondary outcomes measures included clinical success, defined as the absence of post-sclerotherapy fractures or the need for surgical revision, and radiological success, determined by the conversion of an active or aggressive aneurysmal bone cyst to inactive, according to Campanacci's classification.

resultsNo major complications related to the procedure were observed. One minor complication (3.7%) was reported: One local collection resolved with antibiotic therapy. The remaining patients showed favorable clinical and radiological outcomes. No fractures were recorded after sclerotherapy. Surgical revision for progressive recurrence was necessary in 2 cases (7.4%). Aneurysmal bone cyst becoming inactive in 21 of 27 (77.8%) patients after 12 months, 13 of 14 (92.8%) patients after 24 months, and 7 of 7 (100%) and 5 of 5 (100%) patients after more than 36 and 48 months, respectively.

conclusionRadio-opaque gelified ethanol sclerotherapy offers a safe, effective, and minimally invasive treatment for primary aneurysmal bone cyst. It may be considered a first-line approach, similar to other sclerotherapy methods, potentially avoiding the need for invasive surgery as an initial treatment option.

Indexed as

Bone Cysts, AneurysmalEthanolSclerosing SolutionsSclerotherapyAdolescentAdultAgedChildFeasibility StudiesFemaleGelsHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeEthanolGelsSclerosing SolutionsAneurysmal bone cystBone lesionInterventional radiologyMinimally invasive procedureRadio-opaque gelified ethanolSclerotherapy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.