Evidence map›Paper›PMID 39870829›Full record

ArticleSurgical endoscopy2025

Implementation of intraoperative procedures to prevent anastomotic leak in low anterior rectal resections: a pilot study for a novel technique to evaluate anastomotic vascularization.

Monica Ortenzi, Andrea Carsetti, Andrea Picchetto, Giancarlo D'Ambrosio, Erika Casarotta, Alberto Sartori, Andrea Balla, Mauro Podda, Abele Donati, Salvatore Iuorio and 3 more

Abstract read
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Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Monica OrtenziClinica Chirurgica, Department of Experimental and Clinical Medicine, Section of Surgical Sciences, Polytechnic University of Marche, Ancona, Italy. monica.ortenzi@gmail.com.ORCID 0000-0002-6508-6488
Andrea CarsettiClinica di Anestesia e Rianimazione, Università Politecnica delle Marche, Ancona, Italy.
Andrea PicchettoDepartment of General Surgery, Surgical Specialties and Organ Transplantation, Sapienza University of Rome, Rome, Italy.
Giancarlo D'AmbrosioDepartment of General Surgery, Surgical Specialties and Organ Transplantation, Sapienza University of Rome, Rome, Italy.
Erika CasarottaClinica di Anestesia e Rianimazione, Università Politecnica delle Marche, Ancona, Italy.
Alberto SartoriChirurgia Generale, Montebelluna Hospital, Treviso, Italy.
Andrea BallaDepartment of General and Digestive Surgery, University Hospital Virgen Macarena, Seville, Spain.
Mauro PoddaDepartment of Surgical Science, University of Cagliari, Cagliari, Italy.
Abele DonatiClinica di Anestesia e Rianimazione, Università Politecnica delle Marche, Ancona, Italy.
Salvatore IuorioAnestesia e Rianimazione, IRCSS INRCA, Ancona, Italy.
Giovanni LezocheClinica Chirurgica, Department of Experimental and Clinical Medicine, Section of Surgical Sciences, Polytechnic University of Marche, Ancona, Italy.
Alberto ArezzoDepartment of Surgical Sciences, University of Turin, Turin, Italy.
Mario GuerrieriClinica Chirurgica, Department of Experimental and Clinical Medicine, Section of Surgical Sciences, Polytechnic University of Marche, Ancona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAltered vascular microcirculation is recognized as a risk factor for anastomotic leakage (AL) in colorectal surgery. However, few studies evaluated its impact on AL using different devices, with heterogeneous results. The present study reported the initial experience measuring gut microcirculatory density and flow with the aid of incidence dark-field (IDF) videomicroscopy (Cytocam, Braedius, Amsterdam, The Netherlands) comparing its operative outcome using a propensity score matching (PSM) model based on age, gender, and Charlson Comorbidity Index (CCI). MATERIALS AND

methodsVideos from 5 different sites (at least 10 s/site) were recorded from both the mucosal and serosal site of the left colon end after the colonic resection. Total vessel density (TVD), Perfused Vessel Density (PVD), De Backer score, Proportion of Perfused Vessels (PPV), and Microvascular Flow Index (MFI) were analyzed. At each recording, noninvasive measurements of blood pressure, heart rate, temperature, use of vasoactive drugs, and peripheral oxygen saturation were simultaneously recorded. The association between postoperative outcomes and microcirculation evaluation was investigated using PSM analyses.

resultsNinety-nine patients were included in the Cytocam group. The mean TVD small was 8.9 ± 2.8 mm/mm

conclusionThis type of anastomotic evaluation has shown to be feasible, safe, and useful in easily detecting any alteration of the resected colon before anastomotic construction. Moreover, this technology could offer a more cost-effective manner than other devices.

Indexed as

Anastomotic LeakIntraoperative CareProctectomyRectal NeoplasmsRectumAgedAnastomosis, SurgicalColonFemaleHumansMaleMicrocirculationMicroscopy, VideoMiddle AgedPilot ProjectsAnastomosisColorectal surgeryMinimally invasive surgeryVideomicroscopy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.