Evidence map›Paper›PMID 39870815›Full record

ArticleNature medicine2025

Estimating future heat-related and cold-related mortality under climate change, demographic and adaptation scenarios in 854 European cities.

Pierre Masselot, Malcolm N Mistry, Shilpa Rao, Veronika Huber, Ana Monteiro, Evangelia Samoli, Massimo Stafoggia, Francesca de'Donato, David Garcia-Leon, Juan-Carlos Ciscar and 6 more

Abstract read
In one paragraph

Article in Nature medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Building the model: a review of input structures in extreme temperature-health.Environmental health : a global access science source · 2026
    Pooled it
  2. Review
  3. Article
  4. [The oldest old and climate change: an emerging field of research].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2026
    Review
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  19. Harvesting Effect and Extreme Temperature-Related Mortality in Italy.European journal of population = Revue europeenne de demographie · 2026
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Pierre MasselotEnvironment & Health Modelling (EHM) Lab, Department of Public Health Environment & Society, London School of Hygiene & Tropical Medicine, London, UK. pierre.masselot@lshtm.ac.uk.ORCID http://orcid.org/0000-0002-7326-1290
Malcolm N MistryEnvironment & Health Modelling (EHM) Lab, Department of Public Health Environment & Society, London School of Hygiene & Tropical Medicine, London, UK.ORCID http://orcid.org/0000-0003-3345-6197
Shilpa RaoDivision of Climate and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.ORCID http://orcid.org/0000-0003-4012-9063
Veronika HuberDoñana Biological Station, Spanish National Research Council, Seville, Spain.ORCID http://orcid.org/0000-0001-9633-2752
Ana MonteiroDepartment of Geography, University of Porto, Porto, Portugal.ORCID http://orcid.org/0000-0002-3392-2664
Evangelia SamoliDepartment of Hygiene, Epidemiology and Medical Statistics, National and Kapodistrian University of Athens, Athens, Greece.
Massimo StafoggiaDepartment of Epidemiology, Lazio Regional Health Service, ASL ROMA 1, Rome, Italy.
Francesca de'DonatoDepartment of Epidemiology, Lazio Regional Health Service, ASL ROMA 1, Rome, Italy.ORCID http://orcid.org/0000-0002-2225-9457
David Garcia-LeonEuropean Commission, Joint Research Centre, Seville, Spain.ORCID http://orcid.org/0000-0002-3205-7613
Juan-Carlos CiscarEuropean Commission, Joint Research Centre, Seville, Spain.
Luc FeyenEuropean Commission, Joint Research Centre, Ispra, Italy.ORCID http://orcid.org/0000-0003-4225-2962
Alexandra SchneiderInstitute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.ORCID http://orcid.org/0000-0002-1084-2442
Klea KatsouyanniDepartment of Hygiene, Epidemiology and Medical Statistics, National and Kapodistrian University of Athens, Athens, Greece.
Ana Maria Vicedo-CabreraInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Kristin AunanCICERO Center for International Climate Research, Oslo, Norway.ORCID http://orcid.org/0000-0002-7865-9134
Antonio GasparriniEnvironment & Health Modelling (EHM) Lab, Department of Public Health Environment & Society, London School of Hygiene & Tropical Medicine, London, UK.ORCID http://orcid.org/0000-0002-2271-3568

Funding

EC | Directorate-General for Regional Policy (DG Regional Policy) JRC 36206-2022 // DG REGIO 2022CE160AT126EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 Marie Sklodowska-Curie Actions (H2020 Excellent Science - Marie Sklodowska-Curie Actions) 101022870EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 Marie Sklodowska-Curie Actions (H2020 Excellent Science - Marie Sklodowska-Curie Actions) 101032087EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) 820655European Commission (EC) 101022870European Commission (EC) 101032087RCUK | Medical Research Council (MRC) MR/V034162/1Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) TMSGI3_211626
6 · The paper itself

Abstract

Previous health impact assessments of temperature-related mortality in Europe indicated that the mortality burden attributable to cold is much larger than for heat. Questions remain as to whether climate change can result in a net decrease in temperature-related mortality. In this study, we estimated how climate change could affect future heat-related and cold-related mortality in 854 European urban areas, under several climate, demographic and adaptation scenarios. We showed that, with no adaptation to heat, the increase in heat-related deaths consistently exceeds any decrease in cold-related deaths across all considered scenarios in Europe. Under the lowest mitigation and adaptation scenario (SSP3-7.0), we estimate a net death burden due to climate change increasing by 49.9% and cumulating 2,345,410 (95% confidence interval = 327,603 to 4,775,853) climate change-related deaths between 2015 and 2099. This net effect would remain positive even under high adaptation scenarios, whereby a risk attenuation of 50% is still insufficient to reverse the trend under SSP3-7.0. Regional differences suggest a slight net decrease of death rates in Northern European countries but high vulnerability of the Mediterranean region and Eastern Europe areas. Unless strong mitigation and adaptation measures are implemented, most European cities should experience an increase of their temperature-related mortality burden.

Indexed as

Climate ChangeCold TemperatureHot TemperatureMortalityAdultCitiesDemographyEuropeFemaleHumansMaleMiddle Aged

Identifiers

PMID39870815
PMCPMC12003192

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.