Evidence map›Paper›PMID 39870488›Full record

ArticleLearning & memory (Cold Spring Harbor, N.Y.)2025

The influence of exposure to early-life adversity on agency-modulated reinforcement learning.

Hayley M Dorfman, Bryan J W Dong, Katie A McLaughlin, Elizabeth A Phelps

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Learning & memory (Cold Spring Harbor, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hayley M DorfmanDepartment of Psychology, Harvard University, Cambridge, Massachusetts 02138, USA.ORCID http://orcid.org/0000-0001-9865-8158
Bryan J W DongDepartment of Psychology, Harvard University, Cambridge, Massachusetts 02138, USA.
Katie A McLaughlinDepartment of Psychology, Harvard University, Cambridge, Massachusetts 02138, USA.
Elizabeth A PhelpsDepartment of Psychology, Harvard University, Cambridge, Massachusetts 02138, USA phelps@fas.harvard.edu.

Funding

Neurodevelopmental Mechanisms Underlying Stress Vulnerability during AdolescenceR37MH119194 · NIMH · HARVARD UNIVERSITY · PI Katie McLaughlin · 2020 to 2026
$10.6M
Stress, Arousal and Mood: Affective Influences on Decisions under UncertaintyR01DA042855 · NIDA · NEW YORK UNIVERSITY · PI PHELPS, ELIZABETH ANYA · 2017 to 2021
$2.6M
Neurodevelopmental Mechanisms Underlying Stress Vulnerability during AdolescenceR56MH119194 · NIMH · HARVARD UNIVERSITY · PI MCLAUGHLIN, KATIE · 2019 to 2019
$1.5M
NIDA NIH HHS R01 DA042855NIMH NIH HHS R37 MH119194NIMH NIH HHS R56 MH119194
6 · The paper itself

Abstract

Agency beliefs influence how humans learn from different contexts and outcomes. Research demonstrates that stressors, such as exposure to early-life adversity (ELA), are associated with both agency beliefs and learning, but how these processes interact remains unclear. The current study investigated whether exposure to ELA influences agency and interacts with reinforcement learning in adults. Replicating prior behavioral and computational work, ELA resulted in decreased learning, while increased adversity severity was associated with decreased latent agency beliefs. These findings suggest that exposure to adversity in childhood has a nuanced impact on reinforcement learning and agency beliefs in adulthood.

Indexed as

Adverse Childhood ExperiencesReinforcement, PsychologyStress, PsychologicalAdolescentAdultFemaleHumansMaleYoung Adult

Identifiers

PMID39870488
PMCPMC11801475

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.