Evidence map›Paper›PMID 39870399›Full record

ArticleAJNR. American journal of neuroradiology2025

Effect of SARS-CoV-2 Infection on Endovascular Thrombectomy Outcomes-Data from the Florida Stroke Registry.

Hayes B Fountain, Ian Ramsay, Ruijie Yin, Ahmed Abdelsalam, Michael Silva, David Z Rose, Angus Jameson, Ying Hao, Ayham Alkhachroum, Carolina M Gutierrez and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Hayes B FountainFrom the Department of Neurology (H.B.F., I.R., R.Y., A.A., M.S., Y.H., A.A., C.M.G., V.J.D.B., R.M.S., T.R., H.G., J.G.R., N.A.), Miller School of Medicine, University of Miami, Miami, Florida hfountain@med.miami.edu.ORCID https://orcid.org/0000-0002-8635-5878
Ian RamsayFrom the Department of Neurology (H.B.F., I.R., R.Y., A.A., M.S., Y.H., A.A., C.M.G., V.J.D.B., R.M.S., T.R., H.G., J.G.R., N.A.), Miller School of Medicine, University of Miami, Miami, Florida.ORCID https://orcid.org/0000-0003-1896-4337
Ruijie YinFrom the Department of Neurology (H.B.F., I.R., R.Y., A.A., M.S., Y.H., A.A., C.M.G., V.J.D.B., R.M.S., T.R., H.G., J.G.R., N.A.), Miller School of Medicine, University of Miami, Miami, Florida.
Ahmed AbdelsalamFrom the Department of Neurology (H.B.F., I.R., R.Y., A.A., M.S., Y.H., A.A., C.M.G., V.J.D.B., R.M.S., T.R., H.G., J.G.R., N.A.), Miller School of Medicine, University of Miami, Miami, Florida.ORCID https://orcid.org/0000-0001-6651-9030
Michael SilvaFrom the Department of Neurology (H.B.F., I.R., R.Y., A.A., M.S., Y.H., A.A., C.M.G., V.J.D.B., R.M.S., T.R., H.G., J.G.R., N.A.), Miller School of Medicine, University of Miami, Miami, Florida.
David Z RoseUniversity of South Florida Morsani College of Medicine (D.Z.R., A.J.), Tampa, Florida.
Angus JamesonUniversity of South Florida Morsani College of Medicine (D.Z.R., A.J.), Tampa, Florida.
Ying HaoFrom the Department of Neurology (H.B.F., I.R., R.Y., A.A., M.S., Y.H., A.A., C.M.G., V.J.D.B., R.M.S., T.R., H.G., J.G.R., N.A.), Miller School of Medicine, University of Miami, Miami, Florida.
Ayham AlkhachroumFrom the Department of Neurology (H.B.F., I.R., R.Y., A.A., M.S., Y.H., A.A., C.M.G., V.J.D.B., R.M.S., T.R., H.G., J.G.R., N.A.), Miller School of Medicine, University of Miami, Miami, Florida.
Carolina M GutierrezFrom the Department of Neurology (H.B.F., I.R., R.Y., A.A., M.S., Y.H., A.A., C.M.G., V.J.D.B., R.M.S., T.R., H.G., J.G.R., N.A.), Miller School of Medicine, University of Miami, Miami, Florida.
Victor J Del BruttoFrom the Department of Neurology (H.B.F., I.R., R.Y., A.A., M.S., Y.H., A.A., C.M.G., V.J.D.B., R.M.S., T.R., H.G., J.G.R., N.A.), Miller School of Medicine, University of Miami, Miami, Florida.
Robert M StarkeFrom the Department of Neurology (H.B.F., I.R., R.Y., A.A., M.S., Y.H., A.A., C.M.G., V.J.D.B., R.M.S., T.R., H.G., J.G.R., N.A.), Miller School of Medicine, University of Miami, Miami, Florida.
Tanja RundekFrom the Department of Neurology (H.B.F., I.R., R.Y., A.A., M.S., Y.H., A.A., C.M.G., V.J.D.B., R.M.S., T.R., H.G., J.G.R., N.A.), Miller School of Medicine, University of Miami, Miami, Florida.ORCID https://orcid.org/0000-0002-7115-9815
Hannah GardenerFrom the Department of Neurology (H.B.F., I.R., R.Y., A.A., M.S., Y.H., A.A., C.M.G., V.J.D.B., R.M.S., T.R., H.G., J.G.R., N.A.), Miller School of Medicine, University of Miami, Miami, Florida.
Jose G RomanoFrom the Department of Neurology (H.B.F., I.R., R.Y., A.A., M.S., Y.H., A.A., C.M.G., V.J.D.B., R.M.S., T.R., H.G., J.G.R., N.A.), Miller School of Medicine, University of Miami, Miami, Florida.ORCID https://orcid.org/0000-0003-3667-2792
Negar AsdaghiFrom the Department of Neurology (H.B.F., I.R., R.Y., A.A., M.S., Y.H., A.A., C.M.G., V.J.D.B., R.M.S., T.R., H.G., J.G.R., N.A.), Miller School of Medicine, University of Miami, Miami, Florida.ORCID https://orcid.org/0000-0002-0285-825X
Florida Stroke Registry

Funding

The Data Management and BiostatisticsU54NS081763 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ROMANO, JOSE G · 2013 to 2017
$4.2M
NINDS NIH HHS U54 NS081763
6 · The paper itself

Abstract

background and purposeEndovascular thrombectomy outcomes are impacted by changes in stroke systems of care. During the pandemic, SARS-CoV-2 positive status had major implications on hospital arrival and treatment models of non-COVID-related hospital admissions. Using the Florida Stroke Registry, we compared the rates of in-hospital death and discharge outcomes of patients treated with endovascular thrombectomy who tested positive for SARS-CoV-2 infection during their hospitalization. MATERIALS AND

methodsData from Get with the Guidelines-Stroke hospitals participating in the Florida Stroke Registry during the COVID pandemic from March 2020 to December 2022 were reviewed to identify endovascular thrombectomy patients with coding for SARS-CoV-2 testing during their hospital stay. Associations between SARS-CoV-2 status and favorable endovascular thrombectomy outcomes of mRS (0-2) at discharge, discharge to home or rehabilitation center, symptomatic intracerebral hemorrhage, in-hospital mortality, and independent ambulation at discharge were examined by using multivariate logistic regression modeling adjusting for demographics, vascular risk factors, and clinical characteristics. Temporal analyses were used to compare outcomes across the study period.

resultsA total of 8184 patients underwent endovascular thrombectomy (median age 71.1 years, women 49.7%, mean NIHSS 14). Of these, 180 (2.20%) were SARS-CoV-2 positive. Compared with SARS-CoV-2 negative endovascular thrombectomy patients, those who tested positive were younger, more frequently men, but with comparable stroke severity at presentation. In multivariable analysis, adjusting for baseline differences and confounding variables, there was a 33% lower likelihood of being discharged to home/inpatient rehab (OR = 0.67, 95% CI: 0.49-0.93), 65% higher odds of in-hospital death (OR = 1.65, 95% CI: 1.06-2.58), as well as a 91% less chance of having a high mRS (>2) at discharge (OR = 0.15, 95% CI: 0.04-0.60) for patients with positive SARS-CoV-2 infection. However, a similar risk of symptomatic intracerebral hemorrhage was present compared with SARS-CoV-2 negative patients (OR = 0.97, 95% CI: 0.50-1.88). Temporal analysis of SARS-CoV-2 positive patients showed no significant differences.

conclusionsIn this large multicenter stroke registry, despite comparable clinical presentation and treatment timelines, SARS-CoV2 positive status negatively impacted thrombectomy outcomes.

Indexed as

COVID-19Endovascular ProceduresStrokeThrombectomyAgedAged, 80 and overFemaleFloridaHospital MortalityHumansMaleMiddle AgedPatient DischargeRegistriesSARS-CoV-2Treatment Outcome

Identifiers

PMID39870399
PMCPMC12453421

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