Evidence map›Paper›PMID 39869813›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Efficient, scalable, and near-nucleotide-resolution profiling of protein occupancy in the genome with deaminases.

Lei Chang, Bing Ren

Abstract readComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Lei ChangDepartment of Cellular and Molecular Medicine, University of California, San Diego School of Medicine, La Jolla, CA 92093.
Bing RenDepartment of Cellular and Molecular Medicine, University of California, San Diego School of Medicine, La Jolla, CA 92093.

Funding

Center for Multiomic Human Brain Cell AtlasUM1MH130994 · NIMH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI MARIA MARGARITA BEHRENS, Joseph R Ecker · 2022 to 2026
$92.4M
Molecular SignaturesU19MH114831 · NIMH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI CALLAWAY, EDWARD M, ECKER, JOSEPH R · 2017 to 2021
$24.6M
Spatial Mapping Senescent Cells Across the Mouse Lifespan by Multiplex Transcriptomics and EpigenomicsU54AG079758 · NIA · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI PETER D. ADAMS · 2022 to 2026
$12.1M
High throughput CRISPR-mediated functional validation of regulatory elementsUM1HG009402 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI REN, BING, SHEN, YIN · 2017 to 2021
$8.4M
The impact of genomic variation on environment-induced changes in pancreatic beta cell statesU01HG012059 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Hannah Kathryn Carter, Kyle Jeffrie Gaulton · 2021 to 2026
$7.5M
Center for Integrated Multi-modal and Multi-scale Nucleome ResearchUM1HG011585 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DULAC, CATHERINE, LEIN, ED · 2020 to 2024
$6.7M
Epigenomic cell-type classification and regulatory element identification in the human brainU01MH121282 · NIMH · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI BEHRENS, M MARGARITA, ECKER, JOSEPH R · 2019 to 2021
$5.4M
Comparative Single-Cell Epigenomic Analysis of AD-like Pathogenesis in Unconventional Animal ModelsR24AG073198 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI REN, BING, XU, XIANGMIN · 2021 to 2024
$4.8M
Epigenome-based Cell Census and Regulatory Element Discovery in the Aging Mouse BrainR01AG066018 · NIA · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI ECKER, JOSEPH R, REN, BING · 2019 to 2023
$4.6M
Large scale discovery and validation of brain cell type enhancers for viral targeting and circuit manipulationRF1MH124612 · NIMH · DUKE UNIVERSITY · PI DIAO, YARUI, HUANG, Z JOSH · 2020 to 2020
$3.9M
Epigenomic analysis of neural circuits in Alzheimer's disease mouse modelsR01AG067153 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI REN, BING, XU, XIANGMIN · 2020 to 2024
$3.8M
Single-Cell Analysis of Aging-Associated 4D Nucleome in the Human HippocampusU01DA052769 · NIDA · UNIVERSITY OF CALIFORNIA-IRVINE · PI REN, BING, XU, XIANGMIN · 2020 to 2024
$3.4M
HHS | NIH (NIH) 1UM1HG009402 1U19MH114831 1U01MH121282 1R01AG066018 R01AG067153 U01DA052769 1UM1HG011585 RF1MH128838HHS | NIH (NIH) R41MH128993 UM1MH130994 1U54AG079758NEI NIH HHS R01 EY031663NHGRI NIH HHS U01 HG012059NHGRI NIH HHS UM1 HG009402NHGRI NIH HHS UM1 HG011585NIA NIH HHS R01 AG066018NIA NIH HHS R01 AG067153NIA NIH HHS R24 AG073198NIA NIH HHS R56 AG069107NIA NIH HHS U54 AG079758NIDA NIH HHS U01 DA052769NIMH NIH HHS R41 MH128993NIMH NIH HHS RF1 MH124612NIMH NIH HHS RF1 MH128838NIMH NIH HHS U01 MH121282NIMH NIH HHS U19 MH114831NIMH NIH HHS UM1 MH130994
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39869813
PMCPMC11804588

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.