Evidence map›Paper›PMID 39869798›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

How should the advancement of large language models affect the practice of science?

Marcel Binz, Stephan Alaniz, Adina Roskies, Balazs Aczel, Carl T Bergstrom, Colin Allen, Daniel Schad, Dirk Wulff, Jevin D West, Qiong Zhang and 8 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Large language models accurately identify decision reasons in verbal reports.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
  6. Article
  7. The "machinal bypass" and how we're using AI to avoid ourselves.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Article
  9. Counterfeit judgments in large language models.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Unequal Scientific Recognition in the Age of LLMs.Findings of ACL. EMNLP. Conference on Empirical Methods in Natural Language Processing · 2025
    Article
  11. The simulation of judgment in LLMs.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. Article
  13. Article
  14. The benefits and dangers of anthropomorphic conversational agents.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Article
  16. Article
  17. Dialogues about the practice of science.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  18. Automating the practice of science: Opportunities, challenges, and implications.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Marcel Binz *Max Planck Institute for Biological Cybernetics, Tübingen, Baden-Württemberg 72076, Germany.ORCID 0000-0001-8872-8386
Stephan Alaniz *Helmholtz Center for Computational Health, Munich, Oberschleißheim, Bayern 85764, Germany.ORCID 0000-0003-3541-2163
Adina RoskiesDepartment of Psychological and Brain Sciences, University of California, Santa Barbara, CA 93106.
Balazs AczelInstitute of Psychology, Eötvös Loránd University, Budapest 1053, Hungary.ORCID 0000-0001-9364-4988
Carl T BergstromDepartment of Linguistics, University of Washington, Seattle, WA 98195.ORCID 0000-0002-2070-385X
Colin AllenDepartment of Psychological and Brain Sciences, University of California, Santa Barbara, CA 93106.ORCID 0000-0003-4497-1725
Daniel SchadPsychology Department and Institute of Mind, Brain and Behavior, Health and Medical University, Potsdam, Brandenburg 14471, Germany.ORCID 0000-0003-2586-6823
Dirk WulffMax-Planck-Institute for Human Development, Berlin 14195, Germany.
Jevin D WestDepartment of Linguistics, University of Washington, Seattle, WA 98195.ORCID 0000-0002-4118-0322
Qiong ZhangDepartment of Psychology, Rutgers University, New Brunswick, NJ 08901.
Richard M ShiffrinDepartment of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47408.ORCID 0000-0002-3708-3212
Samuel J GershmanDepartment of Psychology, Harvard University, Cambridge, MA 02138.ORCID 0000-0002-6546-3298
Vencislav PopovDepartment of Psychology, University of Zurich, Zurich 8006, Switzerland.ORCID 0000-0002-8073-4199
Emily M Bender *Department of Linguistics, University of Washington, Seattle, WA 98195.ORCID 0000-0001-5384-6227
Marco Marelli *Department of Psychology, University of Milano-Bicocca, Milano 20126, Italy.ORCID 0000-0001-5831-5441
Matthew M Botvinick *Section/Unit, Google DeepMind, London N1C4AG, United Kingdom.
Zeynep Akata *Helmholtz Center for Computational Health, Munich, Oberschleißheim, Bayern 85764, Germany.ORCID 0000-0002-1432-7747
Eric Schulz *Max Planck Institute for Biological Cybernetics, Tübingen, Baden-Württemberg 72076, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Large language models (LLMs) are being increasingly incorporated into scientific workflows. However, we have yet to fully grasp the implications of this integration. How should the advancement of large language models affect the practice of science? For this opinion piece, we have invited four diverse groups of scientists to reflect on this query, sharing their perspectives and engaging in debate. Schulz et al. make the argument that working with LLMs is not fundamentally different from working with human collaborators, while Bender et al. argue that LLMs are often misused and overhyped, and that their limitations warrant a focus on more specialized, easily interpretable tools. Marelli et al. emphasize the importance of transparent attribution and responsible use of LLMs. Finally, Botvinick and Gershman advocate that humans should retain responsibility for determining the scientific roadmap. To facilitate the discussion, the four perspectives are complemented with a response from each group. By putting these different perspectives in conversation, we aim to bring attention to important considerations within the academic community regarding the adoption of LLMs and their impact on both current and future scientific practices.

Indexed as

Diffusion of InnovationLarge Language ModelsScienceHumansAIlarge language modelsscience

Identifiers

PMID39869798
PMCPMC11804466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.