ArticleBrain : a journal of neurology2025
White matter connections within the central sulcus subserving the somato-cognitive action network.
Article in Brain : a journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Article
- Beyond the Homunculus-SCAN-AMN as a Shared Action-Oriented Neural Substrate across Movement Disorders.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Parallel processing chains span cytoarchitectures to organize association cortex.bioRxiv : the preprint server for biology · 2026Article
- Sulcal anatomy of ventral temporal cortex and reading development.bioRxiv : the preprint server for biology · 2026Article
- Characterization of the Central Sulcus Pli-De-Passage Fronto-Pariétal Moyen in > 1000 Human Brains.Human brain mapping · 2026Article
- Functional organization of the primary motor cortex in psychosis and the potential role of intereffector regions in psychomotor slowing.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Neurocomputational Mechanisms of Sense of Agency: Literature Review for Integrating Predictive Coding and Adaptive Control in Human-Machine Interfaces.Brain sciences · 2025Review
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Abstract
The somato-cognitive action network (SCAN) consists of three nodes interspersed within Penfield's motor effector regions. The configuration of the somato-cognitive action network nodes resembles the one of the 'plis de passage' of the central sulcus: small gyri bridging the precentral and postcentral gyri. Thus, we hypothesize that these may provide a structural substrate of the somato-cognitive action network. Using microdissections of 16 human hemispheres, we consistently identified a chain of three distinct plis de passage with increased underlying white matter in locations analogous to the somato-cognitive action network nodes. We mapped localizations of plis de passage into standard stereotactic space to seed functional MRI connectivity across 9000 resting-state functional MRI scans, which demonstrated the connectivity of these sites with the somato-cognitive action network. Intraoperative recordings during direct electrical central sulcus stimulation further identified inter-effector regions corresponding to plis de passage locations. This work provides a critical step towards an improved understanding of the somato-cognitive action network in both structural and functional terms. Furthermore, our work has the potential to guide the development of refined motor cortex stimulation techniques for treating brain disorders and operative resective techniques for complex surgery of the motor cortex.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.