Evidence map›Paper›PMID 39869447›Full record

ArticleMelanoma management2024

Early palliative care in metastatic uveal melanoma (early together): protocol of a prospective randomized Phase III trial.

Sophie Piperno-Neumann, Leanne de Koning, Timothée Marchal, Lauris Gastaud, Lorraine Waechter, Anne Fogliarini, Carole Bouleuc, Yves Libert, Romain Seban, Laura Thery and 6 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Melanoma management, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04728113 (Early Integration of Supportive Care Into Standard Oncology Care for Metastatic Uveal Melanoma Patients), which is not on this map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04728113 nacompletednot on this map

Early Integration of Supportive Care Into Standard Oncology Care for Metastatic Uveal Melanoma Patients

TypeinterventionalSponsorInstitut CurieRan2020 to 2025Enrolled162ConditionsUveal MelanomaArmsSupportive care visit with questionnaires, Oncological standard visit
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Sophie Piperno-NeumannMedical Oncology Dep, Institut Curie, Paris, France.ORCID 0000-0001-9915-2810
Leanne de KoningTranslational Research Dep, Institut Curie, Paris, France.ORCID 0000-0002-8072-3633
Timothée MarchalSupportive Care Dep, Institut Curie, Paris, France.
Lauris GastaudMedical Oncology Dep, Centre Antoine Lacassagne, Nice, France.
Lorraine WaechterUnité mobile de Soins Palliatifs, Hôpital Cochin, Paris, France.
Anne FogliariniSupportive Care Dep, Centre Antoine Lacassagne, Nice, France.
Carole BouleucSupportive Care Dep, Institut Curie, Paris, France.
Yves LibertULB Institut Jules Bordet, Brussels, Belgium.
Romain SebanSupportive Care Dep, Institut Curie, Paris, France.
Laura TherySupportive Care Dep, Institut Curie, Paris, France.
Agnes DucoulombierMedical Oncology Dep, Centre Antoine Lacassagne, Nice, France.
Manuel RodriguesMedical Oncology Dep, Institut Curie, Paris, France.
Anne BredartPsycho-Oncology Service, Supportive Care Department, Institut Curie, SHARE team, PSL University, Paris France.
Alexia SavignoniUnit of Biostatistics, Institut Curie, Paris, France.
Sylvie DolbeaultPsycho-Oncology Service, Supportive Care Department, Institut Curie, SHARE team, PSL University, Paris France.
Alexis BurnodSupportive Care Dep, Institut Curie, Paris, France.

Funding

Cancéropole Ile-de-FranceInstitut National Du Cancer 2019-1-PL SHS-02-ICH-1
6 · The paper itself

Abstract

Metastatic uveal melanoma (UM) patients often initially present with limited symptoms despite a poor prognosis, complicating communication with patients and caregivers. Early Together (NCT04728113) is a randomized Phase III trial that integrates early palliative care through systematic joint visits involving the palliative care team and the medical oncologist, compared with standard oncological care, in 162 metastatic UM patients beginning systemic treatment. This collaboration aims to enhance patient functioning, improve quality of life and facilitate coping mechanisms. Patients' quality of life and needs for information, care and support are assessed over 12 months using validated questionnaires in both groups. Investigators receive training throughout the study to improve communication skills in addressing uncertainty and poor prognosis. This article describes the trial protocol.

Indexed as

communication trainingearly palliative caremetastatic uveal melanomapsychological care needsquality of life

Identifiers

PMID39869447
PMCPMC11318732

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.