Evidence map›Paper›PMID 39869216›Full record

ArticleAbdominal radiology (New York)2025

Impact of anatomical features of non-thrombotic left iliac venous compression on the development of venous leg ulcers based on CT venography.

Fandong Li, Xiaojie Lian, Mengtao Wu, Deqing Zhang, Dianjun Tang, Qiang Sun

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Article in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Fandong Li *Department of Vascular Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Xiaojie Lian *Department of Hand and Foot Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Mengtao WuDepartment of Vascular Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China. wumengtao@163.com.
Deqing ZhangDepartment of Radiology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Dianjun TangDepartment of Vascular Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Qiang SunDepartment of Vascular Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo explore the anatomical features of left iliac vein (LIV) in non-thrombotic venous leg ulcers (VLUs) and to identify the impact of these anatomical features on VLUs based on computed tomography venography (CTV).

methodsThis is a retrospective, single-center study of a database (2021-2023) of 431 patients with non-thrombotic chronic venous insufficiency. According to CEAP clinical (C) classifications, cases of C6 and C2 were included for analysis as case and control groups. Based on CTV data, variables that reflected the anatomical characteristics of LIV and lower lumbar degenerative changes were compared between the two groups. Multivariate logistic regression analysis was performed to evaluate impact of the anatomical features of LIV on VLUs.

resultsA total of 116 patients (group C6 (n = 33) and C2 (n = 83)) were included. Variables including anterior lumbar vertebral osteophytes (ALVO), minimum diameter of LIV, the number of sites of LIV stenosis, proportion of cases with percentage compression of LIV ≥ 75%, proportion of cases with triple or dual LIV stenosis showed significant difference between the two groups (all P ˂0.05). Logistic regression analysis showed ALVO [odds ratio (OR) = 3.852, P = 0.025], number of sites of LIV stenosis [OR = 2.654, P = 0.027] and minimum diameter of LIV [OR = 0.585, P = 0.010] were all significant for VLUs.

conclusionsThe factors of ALVO and number of sites of LIV stenosis were risk factors, whereas minimum diameter of LIV was a protective factor for VLUs. This provided a direction for preoperative planning of non-thrombotic LIV stenting.

Indexed as

Computed Tomography AngiographyIliac VeinPhlebographyTomography, X-Ray ComputedVaricose UlcerVenous InsufficiencyAdultAgedConstriction, PathologicFemaleHumansMaleMiddle AgedRetrospective StudiesCT venographyIliac venous compression syndromeLeg ulcersLumbar vertebral osteophytes

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.