ArticleIrish journal of medical science2025
The triglyceride-glucose index as a surrogate measure to assess glycemic control in type 2 diabetes patients.
Article in Irish journal of medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- First-trimester atherogenic index of plasma and triglyceride-glucose indices in pregestational diabetes mellitus: associations with adverse pregnancy outcomes.BMC pregnancy and childbirth · 2025Article
- Article
- Associations of dietary inflammatory index and composite dietary antioxidant index with erectile dysfunction and the mediating role of metabolic dysregulation: a cross-sectional analysis of NHANES 2001-2004 data.Frontiers in nutrition · 2025Article
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Abstract
backgroundIt has been revealed that the potential utility of the triglycerides and glucose (TyG) index as an effective option for assessing glycemic control; however, evidence in this field is still scarce.
aimsThe goal of this study was to investigate the diagnostic accuracy of the TyG index, as an alternative option, to detect inadequate glycemic control in patients with type 2 diabetes (T2D).
methodsMen and women between 30 and 60 years of age diagnosed with type 2 diabetes were included in a cross-sectional study. Exclusion criteria were smoking, alcohol intake, pregnancy, type 1 diabetes, cancer, autoimmune diseases, active infections, kidney disease, and incomplete data. According to the glycated hemoglobin (HbA1c) concentration, patients were allocated into the groups with optimal (< 7.0%) and deficient (≥ 7.0%) glycemic control.
resultsIn total, 129 patients aged 51.1 ± 6.6 years were included in this study. The logistic regression analysis adjusted by age, sex, body mass index, waist circumference, and time of diabetes diagnosis revealed that the TyG index is strongly associated with deficient glycemic control (OR = 86.6; 95% CI: 12.9 - 576.9). The best cut-off point of the TyG index for identifying inadequate glucose control was 4.93, which showed the highest sensitivity (80%) and specificity (67%) values. Additionally, the positive and negative predictive values were 71% and 74%, while the positive and negative likelihood ratios were 1.68 and 0.41, respectively.
conclusionThe results of our study suggest that the TyG index may be used as an optional test for assessing glycemic control in patients with T2D.
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