Evidence map›Paper›PMID 39869013›Full record

ArticleThyroid : official journal of the American Thyroid Association2025

Strength of Genetic Associations with Thyrotropin Values Differs Between Populations with Similarity to African and European Reference Populations.

Alisha N Wade, Lindsay Guare, Mahtaab Hayat, Peter Straub, Ziyue Gao, Marco Medici, Alexander Teumer, Lea K Davis, Michèle Ramsay, Marylyn D Ritchie and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alisha N WadeResearch in Metabolism and Endocrinology, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-1158-2523
Lindsay GuareDepartment of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Mahtaab HayatSydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Peter StraubDivision of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Ziyue GaoDepartment of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Marco MediciDepartment of Internal Medicine, Division of Endocrinology, Radboud University Medical Center, Nijmegen, Netherlands.
Alexander TeumerDepartment of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.ORCID 0000-0002-8309-094X
Lea K DavisDivision of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Michèle RamsaySydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Marylyn D RitchieDepartment of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Penn Medicine BioBankA list of Penn Medicine BioBank contributors is provided at the end of the manuscript.
Anne R CappolaDivision of Endocrinology, Diabetes and Metabolism, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

Funding

Shared Core: Biobanking, Bioinformatics and Data ManagementU54HG006938 · NHGRI · WITS HEALTH CONSORTIUM (PTY), LTD · PI RAMSAY, MICHELE MICHELE · 2012 to 2022
$12.2M
Midcareer Investigator Award in Patient-Oriented Research in AgingK24AG042765 · NIA · UNIVERSITY OF PENNSYLVANIA · PI CAPPOLA, ANNE R · 2013 to 2024
$1.7M
NIA NIH HHS K24 AG042765NIH HHS U54HG006938
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Black PeopleThyrotropinWhite People3',5'-Cyclic-AMP PhosphodiesterasesAdultBlack or African AmericanFemaleGene FrequencyGenome-Wide Association StudyHumansMaleMiddle AgedPolymorphism, Single Nucleotide3',5'-Cyclic-AMP PhosphodiesterasesPDE8B protein, humanThyrotropingenome-wide association studypopulation ancestrythyrotropin

Identifiers

PMID39869013
PMCPMC13622947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.