Evidence map›Paper›PMID 39868989›Full record

ArticleeLife2025

Operation of spinal sensorimotor circuits controlling phase durations during tied-belt and split-belt locomotion after a lateral thoracic hemisection.

Ilya A Rybak, Natalia A Shevtsova, Johannie Audet, Sirine Yassine, Sergey N Markin, Boris I Prilutsky, Alain Frigon

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Ilya A RybakDepartment of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, United States.ORCID https://orcid.org/0000-0003-3461-349X
Natalia A ShevtsovaDepartment of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, United States.ORCID https://orcid.org/0000-0002-1971-9707
Johannie AudetDepartment of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Centre de Recherche du CHUS, Université de Sherbrooke, Sherbrooke, Canada.
Sirine YassineDepartment of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Centre de Recherche du CHUS, Université de Sherbrooke, Sherbrooke, Canada.
Sergey N MarkinDepartment of Neurobiology and Anatomy, College of Medicine, Drexel University, Philadelphia, United States.
Boris I PrilutskySchool of Biological Sciences, Georgia Institute of Technology, Atlanta, United States.ORCID https://orcid.org/0000-0003-0499-3890
Alain FrigonDepartment of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Centre de Recherche du CHUS, Université de Sherbrooke, Sherbrooke, Canada.ORCID https://orcid.org/0000-0002-9259-2706

Funding

Limb coordination during locomotion before and after spinal cord injuryR01NS110550 · NINDS · GEORGIA INSTITUTE OF TECHNOLOGY · PI BORIS I PRILUTSKY, Ilya A Rybak · 2020 to 2026
$3.9M
Propriopsinal neuron function in normal and post-SCI locomotionR01NS112304 · NINDS · UNIVERSITY OF LOUISVILLE · PI Simon Michael Danner, David SK Magnuson · 2021 to 2026
$3.0M
National Science Foundation 2024414NIH HHS R01 NS110550NINDS NIH HHS R01 NS110550NINDS NIH HHS R01 NS112304
6 · The paper itself

Abstract

Locomotion is controlled by spinal circuits that interact with supraspinal drives and sensory feedback from the limbs. These sensorimotor interactions are disrupted following spinal cord injury. The thoracic lateral hemisection represents an experimental model of an incomplete spinal cord injury, where connections between the brain and spinal cord are abolished on one side of the cord. To investigate the effects of such an injury on the operation of the spinal locomotor network, we used our computational model of cat locomotion recently published in

Indexed as

LocomotionSpinal CordSpinal Cord InjuriesAnimalsCatsComputer SimulationFeedback, SensoryThoracic Vertebraecatcentral pattern generatorcomputational modellocomotionneurosciencespinal cord injury

Identifiers

PMID39868989
PMCPMC11771960

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.