Evidence map›Paper›PMID 39868988›Full record

SynthesisEpilepsia2025

Integrated care for mental health in epilepsy: A systematic review and meta-synthesis by the International League Against Epilepsy Integrated Mental Health Care Pathways Task Force.

Milena Gandy, Wendy Wu, Thomas Woldhuis, Sophie D Bennett, Gaston Baslet, Gerardo Araujo-Filho, Avani C Modi, Markus Reuber, Venus Tang, M Providence Umuziga and 1 more

Abstract readSystematic Review
In one paragraph

Synthesis in Epilepsia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Milena GandySchool of Psychological Sciences, Faculty of Medicine, Health, and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0003-2161-3298
Wendy WuSchool of Psychological Sciences, Faculty of Medicine, Health, and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.
Thomas WoldhuisSchool of Psychological Sciences, Faculty of Medicine, Health, and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.
Sophie D BennettInstitute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK.ORCID https://orcid.org/0000-0002-1076-7112
Gaston BasletBruce W. Carter Department of Veterans Affairs, Miami, Florida, USA.ORCID https://orcid.org/0000-0002-3039-582X
Gerardo Araujo-FilhoDepartment of Neurological Sciences, Psychiatry, and Medical Psychology, Faculdade de Medicina de Sao Jose do Rio Preto, Sao Jose do Rio Preto, Brazil.ORCID https://orcid.org/0000-0001-7112-8456
Avani C ModiCincinnati Children's Hospital Medical Center, Division of Behavioral Medicine and Clinical Psychology, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA.ORCID https://orcid.org/0000-0002-7580-3751
Markus ReuberRoyal Hallamshire Hospital, Academic Neurology Unity, University of Sheffield, Sheffield, UK.ORCID https://orcid.org/0000-0002-4104-6705
Venus TangDepartment of Clinical Psychology, Prince of Wales Hospital, Hospital Authority, Hong Kong; Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, China.
M Providence UmuzigaDepartment of Mental Health Nursing, School of Nursing and Midwifery, College of Medicine and Health Sciences, University of Rwanda, Huye, Rwanda.ORCID https://orcid.org/0000-0002-0237-671X
Heidi M Munger ClaryDepartment of Neurology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.ORCID https://orcid.org/0000-0002-9889-8351

Funding

International League Against Epilepsy
6 · The paper itself

Abstract

Mental health (MH) comorbidities are prevalent among people with epilepsy (PWE), but many experience challenges accessing care. To address this, suggestions have been made to integrate MH care into epilepsy care settings, yet the current approaches, benefits, and implementation determinants to MH care integration are unclear. This review aims to synthesize existing integrated MH care models for PWE to inform the development and planning of future initiatives. We searched Embase, Medline, PsycINFO, and Cochrane for articles that described any activity within a health care setting that addressed MH as routine care for PWE. Year of publication was restricted to 2000 onward. At least two authors reviewed articles and extracted data. Barriers, facilitators, and future recommendations were identified through thematic synthesis using NVivo. Study quality was assessed for articles reporting clinical outcomes. Following review of 7520 abstracts and 596 full-text articles, 65 met eligibility criteria and were included. Most (k = 43, 66%) described routine MH screening, with 11 reporting on uptake and acceptability, which was generally high. Interventions included psychological interventions (k = 23, 35%), psychoeducation (k = 9, 14%), and pharmacotherapy (k = 6, 9%). Thirteen articles (20%) reported on changes in MH outcomes, all of which indicated some improvements in MH, but 33% were rated as poor quality. Thirty-four (52%) articles reported on barriers and facilitators, and 34 (37%) articles provided recommendations for future initiatives. Overall, diverse approaches to integrated MH care for PWE were identified, with promising uptake, acceptability, and impacts on MH outcomes. Qualitative analysis informed a proposed framework for future integrated MH care initiatives. The framework outlines fundamental components of care activities, such as MH screening, psychoeducation, and care pathways, as well as key facilitators for their establishment (e.g., policies, infrastructure, staffing) and effective delivery (e.g., staff incentives, acceptability, evaluation).

Indexed as

Delivery of Health Care, IntegratedEpilepsyMental DisordersMental Health ServicesAdvisory CommitteesHumansMental Healthaccessanxietydepressionneuropsychiatrypsychologyscreeningseizure

Identifiers

PMID39868988
PMCPMC11997915

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.