Evidence map›Paper›PMID 39868926›Full record

ArticleJournal of medical virology2025

NK Count and Natural Cytotoxicity in Immune Nonresponders Versus Responders Living With HIV.

Charlotte Silvestre, Edouard Tuaillon, Maël-Morvan Duroyon, Magali Abrantes, Jenny-Constanza Thibout, Martin Villalba, Marie-Christine Picot, Antoine Gross, Alain Makinson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Charlotte SilvestreIRIM, Université de Montpellier, CNRS, Montpellier, France.ORCID 0009-0005-3151-7488
Edouard TuaillonVirology Department, University Hospital Montpellier & Inserm U1058, University Montpellier, Montpellier, France.
Maël-Morvan DuroyonEpidemiology and Clinical Research Unit, University Hospital Montpellier, Montpellier, France.
Magali AbrantesIRIM, Université de Montpellier, CNRS, Montpellier, France.
Jenny-Constanza ThiboutInfectious Diseases Department, University Hospital Montpellier, Montpellier, France.
Martin VillalbaIRMB, INSERM, CNRS, University Hospital Montpellier, University Montpellier, Montpellier, France.
Marie-Christine PicotEpidemiology and Clinical Research Unit, University Hospital Montpellier, Montpellier, France.
Antoine GrossIRIM, Université de Montpellier, CNRS, Montpellier, France.ORCID 0000-0002-4553-524X
Alain MakinsonInfectious Diseases Department, University Hospital Montpellier & INSERM U1175, University Montpellier, Montpellier, France.ORCID 0000-0003-2817-8444

Funding

This work and CS were supported by Sidaction, a French association fighting against HIV and AIDS, the FHU-InCh (University Hospital Federation of Chronic Infections), and CHU de Montpellier, France.
6 · The paper itself

Abstract

Despite viral suppression with antiretroviral therapy, immune nonresponders (INR) among people living with HIV (PLWH) still have a higher risk of developing AIDS-related and non-AIDS-related complications. Our study aimed to investigate the phenotype and functions of Natural Killer (NK) cells in INR, to better understand underlying mechanisms of immune nonresponse. Our cross-sectional study included PLWH aged over 45 with an undetectable HIV viral load sustained for at least 2 years. Participant CD4

Indexed as

HIV InfectionsKiller Cells, NaturalAgedAntibody-Dependent Cell CytotoxicityAnti-HIV AgentsCD4 Lymphocyte CountCross-Sectional StudiesFemaleHumansMaleMiddle AgedViral LoadAnti-HIV AgentscytotoxicityHIVimmune nonresponsenatural killer cells

Identifiers

PMID39868926
PMCPMC11771562

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.