Evidence map›Paper›PMID 39868785›Full record

ArticleMicrobiology spectrum2025

Environmental and population influences on mummichog (

Lei Ma, Mark E Hahn, Sibel I Karchner, Diane Nacci, Bryan W Clark, Amy Apprill

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lei MaMarine Chemistry & Geochemistry Department, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts, USA.ORCID 0000-0003-1420-7048
Mark E HahnBiology Department, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts, USA.
Sibel I KarchnerBiology Department, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts, USA.
Diane NacciUS Environmental Protection Agency, Office of Research and Development, Center for Environmental Measurement and Modeling, Atlantic Coastal Environmental Sciences Division, Narragansett, Rhode Island, USA.
Bryan W ClarkUS Environmental Protection Agency, Office of Research and Development, Center for Environmental Measurement and Modeling, Atlantic Coastal Environmental Sciences Division, Narragansett, Rhode Island, USA.
Amy ApprillMarine Chemistry & Geochemistry Department, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts, USA.ORCID 0000-0002-4249-2977

Funding

Training CoreP42ES007381 · NIEHS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SHERR, DAVID H · 1995 to 2019
$46.1M
Gene-by-environment interactions that affect exposure-mediated congenital heart diseaseR01ES032323 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HAHN, MARK E, WHITEHEAD, JOHN ANDREW · 2021 to 2025
$3.1M
HHS | NIH | National Institute of Environmental Health Sciences (NIEHS) P42ES007381, R01ES032323Joint Initiative Funds W. Andrew Mellon FoundationNational Science Foundation OCE OCE-1938112NIEHS NIH HHS P42 ES007381NIEHS NIH HHS R01 ES032323Ocean Venture Fund
6 · The paper itself

Abstract

The mummichog, IMPORTANCE: The mummichog fish, a common resident of North America's east coast estuaries, has evolved the ability to survive in waters contaminated with toxic chemicals that would typically be deadly. Our study investigates how living in and adapting to these toxic environments may affect their gut microbiomes. We compared mummichogs from a polluted area in Massachusetts with those from a non-polluted site and found significant differences in their gut microbes. Interestingly, when we raised the next generation of these fish in a lab, these differences disappeared, suggesting that the environment plays a more crucial role in shaping the gut microbiome than genetics. Understanding these changes helps shed light on how animals and their associated microbiomes adapt to pollution, which can inform conservation efforts and our broader understanding of environmental impacts on host-microbe dynamics.

Indexed as

BacteriaFundulidaeGastrointestinal MicrobiomeAnimalsArchaeaFundulus heteroclitusPolychlorinated BiphenylsReceptors, Aryl HydrocarbonRNA, Ribosomal, 16SWater Pollutants, Chemical3,4,5,3',4'-pentachlorobiphenylPolychlorinated BiphenylsReceptors, Aryl HydrocarbonRNA, Ribosomal, 16SWater Pollutants, Chemicalanimal microbiomefishmicrobiomemummichog

Identifiers

PMID39868785
PMCPMC11878049

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.