Evidence map›Paper›PMID 39868445›Full record

ReviewProblemy endokrinologii2024

[The functional role and properties of transcortin in the human body].

A Chevais, M M Gadzhimuradova, D G Beltsevich, A N Romanova, K Sh Begova, H V Bagirova, A K Ebzeeva, G A Melnichenko

Abstract readReviewEnglish Abstract
In one paragraph

Review in Problemy endokrinologii, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

A ChevaisEndocrinology Research Centre.
M M GadzhimuradovaEndocrinology Research Centre.
D G BeltsevichEndocrinology Research Centre.
A N RomanovaEndocrinology Research Centre.
K Sh BegovaEndocrinology Research Centre.
H V BagirovaEndocrinology Research Centre.
A K EbzeevaEndocrinology Research Centre.
G A MelnichenkoEndocrinology Research Centre.

Funding

Non-US Government Research Support type
6 · The paper itself

Abstract

Steroid hormones take an active part in a whole complex of physiological processes that are fundamental for the normal development and functioning of the human body. In the bloodstream steroid hormones are bind with specific transport proteins, in particular with transcortin. The matter of changes in hormone-protein complex in various conditions were actively studied in the second half of the twentieth century, but currently this issue has been taken a back seat by the development of high-precision diagnostic methods of steroid hormones determining. This literature review presents accumulated data on the physicochemical properties of transcortin, genetic factors affecting its synthesis and secretion. Published data on its physiological significance in the human body are analyzed in detail within the framework of not only the "free hormone" hypothesis, but also the reservoir hypothesis. Research results have shown that the synthesis of transcortin has been detected in some extrahepatic tissues, including the adrenal glands, however, its role is unknown.

Indexed as

HormonesTranscortinAdrenal GlandsHumansHormonesTranscortin

Identifiers

PMID39868445
PMCPMC11775720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.