Evidence map›Paper›PMID 39868263›Full record

ArticlebioRxiv : the preprint server for biology2025

Modeling Retinitis Pigmentosa 59:

Mai N Nguyen, Dibyendu Chakraborty, Jeffrey Messinger, David M Sherry, Steven J Fliesler, Steven J Pittler

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Funding

ISOPRENOID METABOLISM IN THE RETINAR01EY007361 · NEI · UNIVERSITY OF SOUTH FLORIDA · PI FLIESLER, STEVEN J. · 1988 to 2015
$4.4M
Development and characterization of mouse models of RP59 DHDDS deficiencyR01EY029341 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FLIESLER, STEVEN J., PITTLER, STEVEN J · 2018 to 2021
$2.2M
Cholesterol homeostasis in the vertebrate retinaR01EY033298 · NEI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Steven J. Fliesler · 2023 to 2026
$1.5M
BLRD VA IK6 BX005787NEI NIH HHS R01 EY007361NEI NIH HHS R01 EY029341NEI NIH HHS R01 EY033298
6 · The paper itself

Abstract

D e h ydro d olichyl d iphosphate s ynthase (DHDDS) is an essential enzyme required for several forms of protein glycosylation in all eukaryotic cells. Surprisingly, three mutant alleles, (

Identifiers

PMID39868263
PMCPMC11761419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.