Evidence map›Paper›PMID 39868216›Full record

ArticlebioRxiv : the preprint server for biology2025

Proteomic profiling of zinc homeostasis mechanisms in

Annaliese Cs Meyer, Matthew R McIlvin, Paloma Lopez, Brian C Searle, Mak A Saito

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Annaliese Cs MeyerWoods Hole Oceanographic Institution, Department of Marine Chemistry and Geochemistry, Woods Hole, MA.ORCID 0000-0001-7642-9100
Matthew R McIlvinWoods Hole Oceanographic Institution, Department of Marine Chemistry and Geochemistry, Woods Hole, MA.ORCID 0000-0002-5301-8365
Paloma LopezWoods Hole Oceanographic Institution, Department of Marine Chemistry and Geochemistry, Woods Hole, MA.ORCID 0009-0009-3046-8281
Brian C SearleOhio State University Medical Center, Department of Biomedical Informatics, Columbus, OH.ORCID 0000-0001-8760-6731
Mak A SaitoWoods Hole Oceanographic Institution, Department of Marine Chemistry and Geochemistry, Woods Hole, MA.ORCID 0000-0001-6040-9295

Funding

Response of the Bacterial Metalloproteome to Environmental ConditionsR01GM135709 · NIGMS · WOODS HOLE OCEANOGRAPHIC INSTITUTION · PI SAITO, MAKOTO · 2020 to 2023
$1.9M
NIGMS NIH HHS R01 GM135709
6 · The paper itself

Abstract

Zinc is central to the function of many proteins, yet the mechanisms of zinc homeostasis and their interplay with other cellular systems remain underexplored. In this study, we employ data-dependent acquisition (DDA) and data-independent acquisition (DIA) mass spectrometry to investigate proteome changes in

Identifiers

PMID39868216
PMCPMC11761036

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.