Evidence map›Paper›PMID 39868151›Full record

ArticlebioRxiv : the preprint server for biology2025

Exploring the Pathogen Profiles of Ancient Feces.

Drew Capone, David Holcomb, Amanda Lai, Karl Reinhard, Joe Brown

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Drew CaponeDepartment of Environmental and Occupational Health, School of Public Health, Indiana University.ORCID 0000-0002-2138-6382
David HolcombDepartments of Environmental Sciences and Engineering, Gillings School of Public Health, University of North Carolina at Chapel Hill.ORCID 0000-0003-4055-7164
Amanda LaiAquaya Institute, Larkspur, California.
Karl ReinhardInstitute of Agriculture and Natural Resources, School of Natural Resources, University of Nebraska-Lincoln.
Joe BrownDepartments of Environmental Sciences and Engineering, Gillings School of Public Health, University of North Carolina at Chapel Hill.ORCID 0000-0002-5200-4148

Funding

Biostatstics for Research in Environmental HealthT32ES007018 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel, Rebecca Fry · 1985 to 2026
$31.3M
NIEHS NIH HHS T32 ES007018
6 · The paper itself

Abstract

Analysis of ancient desiccated feces - termed paleofeces or coprolites - can unlock insights into the lives of ancient people. We collected desiccated feces from caves in the Rio Zape Valley in Mexico (725-920 CE). First, we extracted DNA with methods previously optimized for paleofeces. Then, we applied highly sensitive modern molecular tools (i.e., PCR pre-amplification followed by multi-parallel qPCR) to assess the presence of 30 enteric pathogens. We detected ≥1 pathogen associated gene in each of the ten samples and a mean of 3.9 pathogens per sample. The targets detected included

Identifiers

PMID39868151
PMCPMC11760264

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.