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ArticleFrontiers in psychology2024

The influence of expectations on shame, rumination and cognitive flexibility: an experimental investigation on affect-regulatory characteristics of deceptive placebos.

Leonora Nina Schäfer, Winfried Rief

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in psychology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05372744 (The Influence of Expectations on Affect-regulatory Characteristics of Deceptive Placebos), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05372744 nacompletednot on this map

The Influence of Expectations on Affect-regulatory Characteristics of Deceptive Placebos: An Experimental Investigation

TypeinterventionalSponsorPhilipps University MarburgRan2022 to 2022Enrolled127ConditionsSocial Anxiety, DepressionArmsActive Placebo labelled as antidepressant
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Leonora Nina SchäferDepartment for Clinical Psychology and Psychotherapy, Philipps University Marburg, Marburg, Germany.
Winfried RiefDepartment for Clinical Psychology and Psychotherapy, Philipps University Marburg, Marburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Several studies identified affect-regulatory qualities of deceptive placebos within negative and positive affect. However, which specific characteristics of an affect-regulatory framing impacts the placebo effect has not yet been subject to empirical investigations. In particular, it is unclear whether placebo- induced expectations of direct emotion inhibition or emotion regulation after emotion induction elicit stronger effects in affect regulation. Purpose: The aim of the study was to identify whether specifically framed expectations on the occurrence (antecedent-focused) vs. regulation capability (response-modulating) of affect, induced with an active placebo nasal-spray, have effects on affect-regulatory processes. Because personality traits have been suspected to influence placebo responses and affect regulation, an additional goal of the study was to examine modulating influences of shame proneness, level of depression, experiential avoidance, and emotional control. Methods: Healthy volunteers ( Results: Both antecedent-focused and response-modulating placebo framings influenced changes in state shame ( Conclusion: The results suggest that shame, rumination and cognitive flexibility can be positively influenced by placebo treatment in healthy subjects. Personality traits of emotional control and experiential avoidance influenced the placebo response of the antecedent-focused treatment rationale on outcomes individually. Clinical trial registration: ClinicalTrials.gov, identifier NCT05372744.

Indexed as

affectcognitioncognitivedepressionexpectationplacebo effectruminationshame

Identifiers

PMID39868023
PMCPMC11757295

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.