Evidence map›Paper›PMID 39867820›Full record

ArticleChina CDC weekly2025

A Database on Antibiotics and Antibiotic Resistance in Wastewater and Solid Waste from Pharmaceutical Industry Based on a Systematic Review.

Jingwei Wu, Ziming Han, Xiaomin Ma, Ming Su, Amir Hossein Hamidian, Yu Zhang, Min Yang

Abstract read
In one paragraph

Article in China CDC weekly, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jingwei WuState Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China.
Ziming HanState Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China.
Xiaomin MaAgricultural Information Institute, Chinese Academy of Agricultural Sciences, Beijing, China.
Ming SuState Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China.
Amir Hossein HamidianDepartment of Environmental Science and Engineering, Faculty of Natural Resources, University College of Agriculture & Natural Resources, University of Tehran, Karaj, Iran.
Yu ZhangState Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China.
Min YangState Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Residual antimicrobial agents in wastewater and solid waste from antimicrobial manufacturing facilities can potentially contaminate environments. The World Health Organization has established technical guidelines for managing antimicrobial resistance (AMR) in pharmaceutical wastewater and solid waste. However, the scarcity of publicly available data on antimicrobial manufacturing processes impedes the development of effective mitigation strategies. To address this knowledge gap, we developed a comprehensive database documenting antibiotics and antibiotic resistance genes (ARGs) in actual wastewater and solid waste samples, primarily fermentation residues. Through systematic review methodology, we compiled data from extensive searches of English-language article databases, including Web of Science and PubMed. The database contains data from 270 distinct samples collected across 45 fermentation residue treatment systems and 46 wastewater treatment systems, derived from 70 published English-language articles spanning 2008 to 2024. In operational pharmaceutical facilities, antibiotic concentrations ranged from 82 to 1,663 mg/L in raw wastewater and from 1,000 to 10,182 mg/kg dry matter (DM) in antibiotic fermentation residues. Various treatment technologies demonstrated significant reductions in both antibiotic concentrations and ARG levels within wastes. This database provides the first global perspective on antibiotic and ARG contamination from antibiotic production processes, supporting AMR management initiatives. It establishes a dynamic, continuously updated platform accessible to researchers and industry stakeholders via the link: https://dash.drwater.net/antiboard/.

Indexed as

antibiotic resistancedatabasepharmaceutical industry

Identifiers

PMID39867820
PMCPMC11757902

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.