ArticleInternational review of research in developmental disabilities2024
Considerations for developing syndrome-informed early interventions for children with neurogenetic conditions.
Article in International review of research in developmental disabilities, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed.
- Connection between attention, executive function, episodic memory, and adaptive functioning in young adults with Down syndrome.International journal of developmental disabilities · 2026Article
- Portrait of a Spectrum: Clinical and Genetic Characterization of a Large Cohort of Chromatinopathies-30 Years' Experience From a Third Level Center.Clinical genetics · 2026Article
- Caregiver-reported social foundations and cognitive regulation in toddlers with Down syndrome.Frontiers in psychiatry · 2026Article
- Feasibility and Preliminary Efficacy of an Executive Function Intervention for Young Children With Down Syndrome.Journal of intellectual disability research : JIDR · 2025Article
- Acceptability of a Novel Parent-Mediated Executive Function Intervention for Young Children With Down Syndrome in Italy.Journal of applied research in intellectual disabilities : JARID · 2025Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
New insights regarding the early emergence of phenotypic patterns of strength and challenge in neurogenetic conditions afford the possibility of personalized, anticipatory intervention approaches. The development of novel 'syndrome-informed' interventions, however, should incorporate principles that will maximize the utility of intervention activities for as many children with a given neurogenetic condition as possible. This review examines several of these dimensions, including the use of community-engaged frameworks to ensure feasibility and acceptability of novel interventions; the development of cross-nationally valid approaches that can be readily translated into other languages and cultural contexts; and the use of adaptive interventions designs that allow for the tailoring of intervention pathways based on key child dimensions. A case example of the use of these principles is presented in the context of EXPO, a novel executive function intervention designed for young children with Down syndrome. Implications for future intervention development are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.