ArticlePakistan journal of medical sciences2025
A clinical study on the screening efficacy of six thrombotic markers TAT, PIC, TM, t-PAI-C, D-D, and FDP for hypercoagulable state in pregnant women.
Article in Pakistan journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Diagnostic accuracy of D-dimer for predicting postpartum venous thromboembolism: a systematic review and meta-analysis.Thrombosis journal · 2026Review
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5 authors.
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Abstract
Objective: To investigate the screening efficacy of six thrombotic markers for hypercoagulable state (HCS) in pregnant women, including thrombin-antithrombin III complex (TAT), plasmin-alpha-2 plasmin inhibitor complex (PIC), thrombomodulin (TM), tissue-type plasminogen activator inhibitor complex(t-PAI-C), D-dimer(D-D), and fibrinogen degradation products (FDP). Methods: This was a retrospective study. Eighty-five high-risk pregnant women who underwent antenatal examination at Baoding maternal and Child Health Hospital from December 2022 to September 2023 were included as the observation group, while 85 healthy pregnant women without complications or comorbidities who underwent routine antenatal examinations at our hospital were randomly enrolled as the control group. Analyzed the screening value of these six thrombotic markers in pregnant women at risk of HCS. Results: The levels of TAT, PIC, TM, FDP, and D-D in the observation group were significantly higher than in the control group ( Conclusion: TAT, PIC, TM, t-PAI-C, D-D, and FDP can used for the screening of HCS in pregnant women and have a certain predictive value for high-risk pregnant women.
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